Centre Hospitalier Régional D'orléans

This study tested whether shiatsu, a Japanese finger-pressure therapy, can reduce fatigue in people with axial spondyloarthritis (a type of inflammatory arthritis affecting the spine). 72 adults aged 18 to 70 took part. Researchers measured fatigue using a standard questionnaire …

This study compared high-flow nasal oxygen (HFNO) to standard noninvasive ventilation in 51 people with moderate COPD flare-ups. The goal was to see if HFNO could improve blood oxygen and acid levels over 24 hours. Researchers also tracked safety and whether patients needed a bre…

This study looked at whether a serotonin receptor called 5-HT7 could serve as a biomarker for multiple sclerosis (MS). Researchers measured the receptor on immune cells in blood samples from 100 people, including healthy volunteers and MS patients on stable treatment. The goal wa…

This study looked at 40 children aged 6 to 17 with inflammatory bowel disease (IBD) to understand how DNA that escapes from cells might worsen inflammation. Researchers analyzed blood, stool, and gut tissue samples to study a specific pathway called cGAS-STING. The goal was to id…

This study followed 187 people who had COVID-19 for two years to see how their antibody levels changed over time. Researchers also looked at whether the severity of the infection or other patient factors affected antibody persistence. The goal was to better understand long-term i…

This study tested whether a near-infrared light device helps nurses insert IVs more successfully on the first try in ICU patients with swollen arms. 380 adults who no longer needed a central line were randomly assigned to either the light device or the traditional feel-and-look m…

This study looked at whether taking out the nasogastric feeding tube right after a breathing tube is removed helps ICU patients start eating by mouth sooner. Swallowing problems are common after ICU stays, and the feeding tube itself may make things worse. The trial involved 112 …

This study looked at whether special imaging techniques can predict how knee osteoarthritis will get worse over three years. Researchers used MRI, X-rays, and bone texture analysis to examine the bone beneath the cartilage in 167 people with knee osteoarthritis. The goal was to i…

This study looked at how well the Pfizer COVID-19 vaccine works in adults with weakened immune systems (like kidney transplant patients, people with cancer, or those on dialysis) compared to healthy adults. Researchers measured antibody levels and their ability to neutralize the …

This study looked at brain activity in 29 healthy, right-handed adults while they either moved their right hand or felt a vibration that created an illusion of movement. The goal was to figure out the smallest number of repetitions needed to get clear brain signals. The results w…

This study looked at whether talking with a hospital pharmacist can help lung cancer patients on chemotherapy, immunotherapy, or targeted pills avoid unplanned doctor visits or hospital stays. Researchers followed 60 patients for 6 months and counted how many unscheduled consulta…

This study tracked 175 critically ill adults who needed to be moved within the hospital (for example, to get a CT scan) while receiving high-flow nasal oxygen. The goal was to see how often serious problems, like needing a breathing tube or very low oxygen levels, happened during…