Boehringer Ingelheim

This study tested a new medicine called survodutide to help people with overweight or obesity and type 2 diabetes lose weight. About 755 adults took part, receiving either the drug or a placebo injection once a week for 76 weeks, along with diet and exercise advice. The main goal…

This study tested the safety of an experimental drug called BI 770371 in 28 adults with compensated cirrhosis (liver scarring) due to MASH, a fatty liver disease. Participants received either the drug or a placebo as an IV infusion every 3 weeks for 12 weeks. The main goal was to…

This study tested a medicine called survodutide in 218 adults with overweight or obesity and a liver condition called NASH (fatty liver with inflammation). Participants received weekly injections of survodutide or a placebo for about a year, along with diet and exercise advice. T…

This study tested an experimental oral medicine called Avenciguat (BI 685509) in 214 adults with progressive systemic sclerosis (scleroderma), a disease that causes skin thickening and can damage the lungs. Participants took either the drug or a placebo three times daily for at l…

This study looked at the long-term safety of a medicine called nintedanib in children and teenagers (ages 6-17) with a lung condition that causes scarring (fibrosing interstitial lung disease). All participants took nintedanib capsules twice a day for at least 1.5 to 3 years. The…

This study looked at 52 patients in Japan with generalized pustular psoriasis (GPP), a rare and severe skin disease, who received a new treatment called spesolimab. Researchers monitored side effects and how the disease behaved in real-world clinics, not just in controlled trials…

This study tested an experimental drug called BI 655130 in 51 adults with moderate to severe atopic dermatitis (eczema). The goal was to see if the drug is safe and can improve skin symptoms compared to a placebo. Participants received multiple doses of the drug or a placebo by I…

This study tested a single intravenous dose of spesolimab in 53 adults with generalized pustular psoriasis (GPP) experiencing a moderate-to-severe flare. The main goal was to see if the drug could clear visible pustules within one week compared to a placebo. Results showed that s…

This study tested a daily tablet called iclepertin in 620 adults with schizophrenia to see if it could improve memory and thinking skills, like remembering things or paying attention. Participants took either iclepertin or a placebo for 26 weeks while continuing their usual schiz…

This early-stage study tested a new drug called BI 706321 in 73 healthy men to see if it is safe and how the body processes it. Participants received single rising doses of the drug or a placebo. The goal was to gather safety information and measure drug levels in the blood, not …

This early-stage trial tested a single dose of BI 1015550 in 24 healthy Chinese adults to see how the drug is processed by the body and whether it is safe. Participants were monitored for side effects and drug levels in the blood. Since this is a Phase 1 study in healthy people, …

This study looked at whether taking multiple doses of an experimental drug called BI 1015550 changes how the body breaks down another drug, midazolam. Fifteen healthy men took midazolam alone and then again after taking BI 1015550. The goal was to see if BI 1015550 speeds up or s…

This study looked at how taking the antibiotic erythromycin changes the amount of a new drug, BI 1291583, in the blood. Twenty healthy adults took both drugs in a fixed order. The goal was to see if the antibiotic affects how the body processes the new drug, which helps guide fut…

This study looked at how taking multiple doses of zongertinib changes the way the body processes three other drugs: midazolam, omeprazole, and repaglinide. Sixteen healthy men took these drugs alone and then again while on zongertinib. The goal was to see if zongertinib affects t…

This study checked whether zongertinib tablets made by two different manufacturers are absorbed the same way in the body. Fifty-six healthy adults took a single dose of each version at different times. The goal was to see if the two versions are bioequivalent, meaning they work t…

This study looked at how the experimental brain drug iclepertin is processed in people with mild to moderate liver problems compared to those with healthy livers. 29 adults took a single tablet, and researchers measured drug levels in the blood. The goal was to see if liver impai…

This study tested whether taking the experimental drug Zongertinib with or without food changes how much of it gets into the blood. Sixteen healthy men each took one dose under both conditions. The results will help doctors decide the best way to give the drug in future trials.

This study followed 158 adults with chronic fibrosing interstitial lung disease (a type of progressive lung scarring) who were starting the medication nintedanib. Researchers wanted to see if changes in lung function (measured by how much air a person can forcefully exhale) over …

This early-stage study looked at how much of the experimental drug BI 425809 gets into the bloodstream when taken as a pill compared to a tiny intravenous dose. Six healthy men participated to help researchers understand the drug's absorption and processing. The results will guid…

This early-stage trial looked at how taking multiple doses of bosentan changes the amount of BI 425809 in the blood of 14 healthy men. The goal was to measure drug levels, not to treat any disease. Results will help guide future dosing of BI 425809 when used with bosentan.

This study aimed to create a tool that helps doctors decide which rheumatoid arthritis patients should get a CT scan to check for lung disease. Over 1300 adults with rheumatoid arthritis and at least two risk factors (like being male, a smoker, or older than 60) took part. Resear…

This completed Phase 1 trial studied how the experimental drug BI 1015550 is absorbed when taken as a tablet. Eight healthy men received both an oral tablet and a tiny intravenous radioactive tracer dose. The goal was to measure the drug's bioavailability — how much reaches the b…

This study looked at how different levels of kidney function affect the way the experimental brain drug iclepertin is processed in the body. 36 adults with normal or impaired kidneys took a single dose of iclepertin. Researchers measured drug levels in the blood and monitored saf…

This study looked at whether a new weight-loss injection (BI 456906) changes how the body processes three common drugs: bupropion (an antidepressant), caffeine, and midazolam (a sedative). Thirty-four healthy adults with overweight or obesity took these drugs alone and then again…

This early-stage study tested a single dose of a new drug called BI 3006337 in 80 healthy men. The main goal was to check if the drug is safe and how the body processes it. No treatment for any disease was evaluated.

This study looked at whether taking the experimental drug BI 1015550 with food changes how the body absorbs it. 18 healthy adults took the drug once with a meal and once without, and researchers measured drug levels in their blood. The goal was to understand if food affects the d…

This study looked at whether taking a new drug (BI 425809) with food changes how the body absorbs it. Sixteen healthy adults took the drug once with a meal and once on an empty stomach. Researchers measured drug levels in the blood to see if food made a difference. The results wi…

This study looked at how the drug BI 1291583 is broken down and removed from the body. Eight healthy men took a single dose with a radioactive label, and researchers measured the drug and its byproducts in their blood, urine, and stool over several weeks. The goal was to understa…

This completed Phase 1 trial in 16 healthy men tested whether taking carbamazepine (a seizure medicine) changes how the body absorbs and processes nerandomilast, an experimental drug for lung fibrosis. Participants received a single dose of nerandomilast with and without multiple…