New eczema drug shows promise in early trial

NCT ID NCT03822832

First seen Nov 01, 2025 · Last updated Apr 25, 2026 · Updated 12 times

Summary

This study tested an experimental drug called BI 655130 in 51 adults with moderate to severe atopic dermatitis (eczema). The goal was to see if the drug is safe and can improve skin symptoms compared to a placebo. Participants received multiple doses of the drug or a placebo by IV, and researchers measured changes in eczema severity over 16 weeks.

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Contacts and locations

Locations

  • Aichi Medical University Hospital

    Aichi, Nagakute, 480-1195, Japan

  • Center for Clinical Studies

    Webster, Texas, 77598, United States

  • Center for Dermatology and Plastic Surgery

    Scottsdale, Arizona, 85260, United States

  • Clinical Physiology Associates

    Fort Myers, Florida, 33912, United States

  • Dermatology Treatment and Research Center, PA

    Dallas, Texas, 75230, United States

  • Finlay Medical Research Corp

    Miami, Florida, 33126, United States

  • ForCare Clinical Research, Inc.

    Tampa, Florida, 33613, United States

  • Hosui General Medical Clinic

    Hokkaido, Sapporo, 064-0807, Japan

  • Innovaderm Research Inc.

    Montreal, Quebec, H2X 2V1, Canada

  • Kurume University Hospital

    Fukuoka, Kurume, 830-0011, Japan

  • Nagasaki University Hospital

    Nagasaki, Nagasaki, 852-8501, Japan

  • National Hospital Organization Kyushu Medical Center

    Fukuoka, Fukuoka, 810-8563, Japan

  • NewLab Clinical Research Inc.

    St. John's, Newfoundland and Labrador, A1C 2H5, Canada

  • Osaka City University Hospital

    Osaka, Osaka, 545- 8586, Japan

  • Progressive Clinical Research

    San Antonio, Texas, 78213, United States

  • Showa University Hospital

    Tokyo, Shinagawa-ku, 142-8666, Japan

  • Tennocho Ekimae Dermatology and Allergology

    Kanagawa, Yokohama, 240-0004, Japan

  • The Indiana Clinical Trials Center, PC

    Plainfield, Indiana, 46168, United States

  • Tokyo Medical University Hachioji Medical Center

    Tokyo, Hachioji, 193-0998, Japan

  • Unity Clinical Research

    Oklahoma City, Oklahoma, 73118, United States

  • University Hospital Kyoto Prefectural University of Medicine

    Kyoto, Kyoto, 602-8566, Japan

  • University of Alberta Hospital (University of Alberta)

    Edmonton, Alberta, T6G 2B7, Canada

  • University of South Florida

    Tampa, Florida, 33612, United States

Conditions

Explore the condition pages connected to this study.