VASCULAR DISEASES

This large study aimed to see if taking two blood-thinning medications (clopidogrel plus aspirin) is better than taking aspirin alone for patients with multi-vessel heart disease who have received a stent. It involved 8,250 patients across 100 centers and followed them for at lea…

This study tested whether adding a new drug called ralinepag to standard treatments could help people with pulmonary arterial hypertension (PAH), a serious lung and heart condition. It involved 687 adults with PAH who were already on stable medication. The main goal was to see if…

This small pilot study tested whether it's practical and helpful to use stricter blood pressure targets for new mothers who had high blood pressure during pregnancy. It compared keeping blood pressure under 135/85 (tight control) to the usual target of under 150/100. The goal was…

This study tested if a medical procedure could safely lower blood pressure in people whose high blood pressure wasn't controlled by up to three standard medications. Doctors used a special device to disrupt tiny nerves near the kidneys, which are thought to play a role in regulat…

This study tested if a step-by-step checklist (the YEARS algorithm) could safely rule out dangerous blood clots in the lungs of cancer patients without always needing a CT scan. It compared this method to the standard approach of doing a CT scan for everyone. The goal was to see …

This study aimed to understand why Black Americans have higher rates of high blood pressure and heart disease. Researchers tested if taking a daily antioxidant supplement called MitoQ for 8 weeks could improve blood vessel function and lower blood pressure in middle-aged and olde…

This study aimed to better understand how specific inherited gene changes affect the health of people with connective tissue conditions. Researchers observed 32 participants, aged 2 to 100, who already had a known gene change. Over a 3-5 day visit, participants underwent various …