TYMPANIC MEMBRANE PERFORATION
Clinical trials for TYMPANIC MEMBRANE PERFORATION explained in plain language.
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Breakthrough gel could fix eardrums without surgery
⭐️ CURE ⭐️ CompletedThis study tested whether a gel containing a natural growth factor (FGF-2) could heal long-standing holes in the eardrum. 57 adults with chronic perforations applied the gel or a placebo up to three times. The main goal was to see if the gel could safely and effectively close the…
Matched conditions: TYMPANIC MEMBRANE PERFORATION
Phase: PHASE2 • Sponsor: D. Bradley Welling, MD, PhD • Aim: ⭐️ CURE ⭐️
Last updated Mar 24, 2026 12:02 UTC
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Ear surgeons test which patch method heals hearing best
Disease control CompletedThis study compared two ways surgeons patch holes in the eardrum caused by long-term ear infections. Doctors tested whether placing the repair tissue between eardrum layers (interlay) or underneath them (underlay) works better. They measured which technique helped patients hear b…
Matched conditions: TYMPANIC MEMBRANE PERFORATION
Phase: NA • Sponsor: Shaikh Zayed Hospital, Lahore • Aim: Disease control
Last updated Apr 01, 2026 14:43 UTC
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Study checks success of Pig-Based patch for healing eardrum holes
Disease control CompletedThis study collected real-world data on a medical graft used to repair holes in the eardrum (tympanic membrane perforation). It followed 87 patients for up to 3 months after their procedure to see what percentage achieved complete closure of the hole. The goal was to understand h…
Matched conditions: TYMPANIC MEMBRANE PERFORATION
Sponsor: Cook Research Incorporated • Aim: Disease control
Last updated Mar 31, 2026 12:12 UTC
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Growth factor gel trial aims to mend eardrums without surgery
Disease control CompletedThis study tested whether a gel containing a natural growth factor (FGF-2) could help heal long-standing holes in the eardrum. Fifty-two adults with perforations that hadn't healed for at least six months were randomly assigned to receive either the active gel or a placebo gel. T…
Matched conditions: TYMPANIC MEMBRANE PERFORATION
Phase: PHASE2 • Sponsor: NYU Langone Health • Aim: Disease control
Last updated Mar 30, 2026 14:34 UTC
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Doctors look back to perfect Kids' ear surgeries
Disease control CompletedThis study looked back at the medical records of 980 children who had surgery to repair a hole in their ear drum. The goal was to understand what factors, like a child's age or other health conditions, lead to a successful surgery where the eardrum stays closed and hearing improv…
Matched conditions: TYMPANIC MEMBRANE PERFORATION
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Disease control
Last updated Mar 16, 2026 15:24 UTC