Insulin gel mends ear drums faster in small trial

NCT ID NCT07535827

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-phase trial tested a special insulin gel applied directly to the ear drum after surgery to repair a long-standing hole. Fifty adults with dry ear drum perforations received either the insulin gel or a plain foam control. The insulin group showed significantly better healing at follow-ups up to two months. While promising, the study is small and early, so more research is needed.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

insulin gel (applied directly to the ear drum)

What this could lead to

If confirmed in larger trials, this insulin gel could become a simple, low-cost way to help ear drum perforations heal faster after surgery.

What could go wrong

This was a very small, early-phase trial (50 people). The results need to be repeated in larger, longer studies before we know if it really works safely.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

chronic tubotympanic suppurative otitis media Insulin Resistance Tympanic Membrane Perforation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Minia university hospital

    Minya, Egypt