Pig-Derived patch could simplify eardrum surgery

NCT ID NCT07698171

First seen Jul 13, 2026 · Last updated Jul 14, 2026 · Updated 1 time

Summary

This study looks at whether a commercially available graft made from pig intestinal tissue (Biodesign) works as well as a patient's own tissue for closing a hole in the eardrum. Researchers will review medical records of 60 people who had eardrum repair surgery to compare closure rates, hearing improvement, and operating time between the two graft types. The goal is to see if the ready-made graft can be a safe and effective alternative that may shorten surgery time.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Porcine small intestinal submucosa graft (Biodesign)
What this could lead to
If Biodesign works as well as a patient's own tissue, it could offer a simpler, faster surgical option for repairing eardrum holes without needing to harvest the patient's own tissue.
What could go wrong
This is a small, retrospective study, so results may not apply to everyone. The porcine graft might not close the hole as effectively or could cause unexpected reactions.

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Conditions

The condition(s) this trial relates to.

Tympanic Membrane Perforation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Wolfson Medical Center

    Holon, 5822012, Israel

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