New Pig-Tissue patch shows promise for fixing eardrums

NCT ID NCT04635228

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tested a special graft made from pig tissue to close holes in the eardrum. Researchers followed 87 patients for 3 months after the graft was placed to see how many had complete healing. The goal was to find out if this material works well for repairing eardrum perforations.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Biodesign Otologic Repair Graft (a porcine-derived material used as a patch for the eardrum)

What this could lead to

If successful, this graft could offer a reliable way to repair eardrum perforations, potentially improving hearing and reducing ear infections.

What could go wrong

This is a small, post-market study with no comparison group, so results may not apply to everyone. The graft is made from pig tissue, which could cause allergic reactions in sensitive individuals.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Tympanic Membrane Perforation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Children's Hospital of Philadelphia

    Philadelphia, Pennsylvania, 19104, United States

  • Cincinnati Children's Hospital

    Cincinnati, Ohio, 45229, United States

  • Gloucestershire Royal Hospital

    Gloucester, GL 3NN, United Kingdom

  • IU Health

    Indianapolis, Indiana, 46202, United States

  • University Hospitals-Cleveland

    Cleveland, Ohio, 44106, United States