TREATMENT-RESISTANT MAJOR DEPRESSIVE DISORDER
Clinical trials for TREATMENT-RESISTANT MAJOR DEPRESSIVE DISORDER explained in plain language.
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Fast brain stimulation shows promise for stubborn depression
Symptom relief CompletedThis study tested an accelerated form of transcranial magnetic stimulation (TMS) in 50 adults with treatment-resistant depression. Participants received 50 sessions over two weeks, comparing a bilateral approach (stimulating both sides of the brain) with a unilateral one (stimula…
Matched conditions: TREATMENT-RESISTANT MAJOR DEPRESSIVE DISORDER
Phase: NA • Sponsor: Ataturk University • Aim: Symptom relief
Last updated Jun 27, 2026 13:03 UTC
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Anesthetic drug shows promise for tough depression in early trial
Symptom relief CompletedThis early study tested whether a carefully controlled dose of propofol, a common anesthetic, could safely boost brain slow waves in 16 older adults with treatment-resistant depression. Participants received two propofol infusions days apart while researchers monitored brain acti…
Matched conditions: TREATMENT-RESISTANT MAJOR DEPRESSIVE DISORDER
Phase: PHASE1 • Sponsor: Washington University School of Medicine • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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Brain-Zap tech gets a GPS: virtual navigation aims to boost TMS for tough depression
Symptom relief CompletedThis study tested a virtual navigation system to help guide Transcranial Magnetic Stimulation (TMS) for people with treatment-resistant depression. The system aims to personalize the brain target for each patient. Twenty-two adults with major depressive disorder who had not respo…
Matched conditions: TREATMENT-RESISTANT MAJOR DEPRESSIVE DISORDER
Phase: NA • Sponsor: Soterix Medical • Aim: Symptom relief
Last updated Jun 27, 2026 07:52 UTC