Anesthesia waves may lift depression in older adults

NCT ID NCT04680910

First seen Apr 28, 2026 ยท Last updated Apr 28, 2026

Summary

This early study tested whether a carefully controlled dose of propofol (a drug used for sedation) could safely create specific brain waves in people over 60 with hard-to-treat depression. Sixteen participants received two infusions days apart. The main goal was to check safety and see if the drug could boost slow brain waves during sleep, which are often low in depression.

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Contacts and locations

Locations

  • Washington University School of Medicine/Barnes-Jewish Hospital

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.