Brain-Zap tech gets a GPS: virtual navigation aims to boost TMS for tough depression
NCT ID NCT04956081
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study tested a virtual navigation system to help guide Transcranial Magnetic Stimulation (TMS) for people with treatment-resistant depression. The system aims to personalize the brain target for each patient. Twenty-two adults with major depressive disorder who had not responded to at least two prior treatments took part. The goal was to see if this approach could reduce depression symptoms.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Soterix Medical, Inc.
Woodbridge, New Jersey, 07095, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Transcranial Magnetic Stimulation (TMS) device
What this could lead to
If this works, it could make TMS more effective for people with hard-to-treat depression by better targeting the right brain area.
What could go wrong
This was a small, early-phase study with only 22 people, so results may not apply to everyone. The technology is still experimental and may not improve outcomes significantly.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.