TOBACCO USE DISORDER

This study tests whether personalized text messages can motivate people living with HIV in Vietnam to quit smoking. Participants receive motivational texts over six months and are encouraged to use a free government quitline that provides nicotine patches. The goal is to see if t…

This study tests a smoking cessation program called All Nations Breath of Life, designed specifically for American Indian communities. It involves 576 participants at four sites—two on reservations and two in urban areas. The program includes counseling and support, and success i…

This study tests a telephone-based version of the All Nations Breath of Life program, designed specifically for American Indians who smoke. Participants receive coaching calls over the phone and are compared to those in a general smoking cessation program. The main goal is to see…

This study looks at whether helping both patients and their household members quit smoking together works better than helping patients alone. About 231 patients who smoke and live with other smokers will get nicotine replacement therapy and support. Researchers will check quit ra…

This study tests a simple alert built into hospital electronic health records. When a doctor writes a note for a patient who smokes, the alert automatically suggests prescribing nicotine replacement therapy and ordering lung cancer screening. The goal is to see if this reminder h…

This study looks at whether offering money can help hospitalized smokers quit. Over 1,000 adult smokers will be given different types of financial rewards to see which approach works best. The goal is to find a cost-effective way to help people stop smoking for good.

This study tests whether an online training program helps people who recently quit smoking stay smoke-free and also support others in their social network to quit. About 940 adults who have been smoke-free for 2 to 8 weeks will take part. They will complete online surveys and pro…

This pilot study tests whether giving the smoking-cessation drug varenicline to people with HIV who also have alcohol use disorder is practical and safe. Thirty participants will receive the medication along with support from a pharmacist and psychiatrist. The goal is to see if t…

This study tests whether offering financial incentives through a mobile phone app can help low-income adults quit smoking. 532 participants will receive either standard care (phone counseling and nicotine patches/gum) or standard care plus mobile rewards for verified abstinence. …

This study looks at whether varenicline (a prescription drug) or nicotine patches help people quit smoking more effectively, depending on their natural levels of emotion and attention. About 204 smokers aged 18-75 who smoke at least 5 cigarettes daily will receive behavioral coun…

This study tests a program to help people living with HIV in Botswana stop smoking. It combines counseling with a medication called varenicline. The goal is to see if this approach helps them quit and improves their health. The study involves 750 participants who are daily smoker…

This trial tests a digital program designed to help people quit tobacco. Over 2,200 participants will use the program or receive usual care. The main goal is to see if the program helps people stop using their primary tobacco product for at least 30 days.

This study is creating and testing a program to help Hispanic/Latino high school students stop using e-cigarettes. Researchers will work with 120 teens to see if the program is practical and helps reduce vaping. The goal is to support a group that is often overlooked in quitting …

This trial tests whether a school-based program can help parents stop smoking. About 700 families with a smoking parent will take part. The program includes education, motivation support, and relapse prevention delivered both in person and online. Success is measured by whether p…

This study tests whether special lights and cameras can help find early signs of mouth cancer in people at high risk. About 338 participants with precancerous spots or conditions like Fanconi anemia will have their mouths examined with fluorescence imaging, which makes abnormal c…

This study tests whether a type of counseling called behavioral activation therapy, combined with a nicotine patch, helps people quit smoking. It focuses on smokers who have low reward sensitivity, meaning they get less pleasure from rewards. About 85 participants will receive ei…

This study tests whether a smartphone app designed for people with serious mental illness can help them quit smoking. About 64 adults who smoke heavily and have a mental illness will use one of two special apps or a standard app for 5 weeks. All participants also get nicotine pat…

This study tests a 6-session virtual program called Future Self-BD for adults with bipolar disorder who want to quit smoking. Participants are guided to vividly imagine positive future events that could result from quitting, combined with brief smoking cessation counseling. The t…

This pilot study tests whether two smartphone apps can help current smokers quit. 24 participants will use either the KickAsh app (to track mood and activity) or the Breathe2Relax app (for relaxation). Researchers will check if the apps improve mood, increase activity, and lead t…

This study tests a program that combines mood management with health and wellness coaching to help pregnant smokers who are depressed quit smoking and stay smoke-free after their baby is born. About 26 participants will take part during pregnancy and after birth. The goal is to s…

This study tests whether a pharmacist-led program can help low-income smokers use nicotine patches or lozenges to quit or reduce smoking. About 100 adults from community health centers will receive counseling sessions and text support. The goal is to see if this approach is pract…

This study tests whether a short group therapy program (CBT) can help men in prison stop smoking. 202 participants will be randomly assigned to CBT, a health education session, or a waitlist. Researchers will check if they quit by measuring carbon monoxide levels at 1 and 3 month…

This study tests whether doing clinical trial visits remotely (from home) works as well as coming into a clinic. About 200 adults will be randomly assigned to remote or in-person groups for intake and follow-up over 3 months. The goal is to see which method is better at keeping p…

This study tests a program called ENHANCE-TTS that trains pharmacists at HIV clinics to provide tobacco treatment. Researchers will see if the program helps pharmacists offer more smoking cessation services and if it helps patients quit. About 172 people from six clinics will tak…