Could a Stop-Smoking drug curb heavy drinking in HIV patients?
NCT ID NCT06006143
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This pilot study tests whether giving the smoking-cessation drug varenicline to people with HIV who also have alcohol use disorder is practical and safe. Thirty participants will receive the medication along with support from a pharmacist and psychiatrist. The goal is to see if this approach can reduce alcohol use, but the study is small and early, so results will be preliminary.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
varenicline
What this could lead to
If this works, it could point toward a practical way to help people with HIV reduce heavy drinking using an existing medication.
What could go wrong
This is a very small pilot study with only 30 participants, no placebo group, and it's not designed to prove the drug works. The medication is being used off-label, so unexpected side effects are possible.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Atlanta VA Medical Center
Decatur, Georgia, 30033, United States