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New study aims to help HIV patients in botswana kick the habit

NCT ID NCT05694637

ENROLLING_BY_INVITATION Disease control Sponsor: University of Maryland, Baltimore Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a program to help people living with HIV in Botswana stop smoking. It combines counseling with a medication called varenicline. The goal is to see if this approach helps them quit and improves their health. The study involves 750 participants who are daily smokers and on HIV treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
varenicline
What this could lead to
If successful, this could provide an effective, scalable way to help people with HIV quit smoking, reducing HIV complications and deaths.
What could go wrong
This is a phase 4 trial, but results may not apply to all populations. Adherence to medication and counseling can be challenging, and the intervention may not work for everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

AIDS HIV infectious disease nicotine dependence Smoking Cessation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HIV SMOKING CESSATION

Contacts and locations

Locations

  • Airstrip Clinic

    Mahalapye, Central District, Botswana

  • Goodhope Primary Hospital

    Good Hope, Botswana

  • Itekeng Clinic

    Francistown, Central District, Botswana

  • Kanye Adventist Hospital

    Kanye, Botswana

  • Kediretswe Clinic

    Palapye, Botswana

  • Mahalapye District Hospital

    Mahalapye, Central District, Botswana

  • Masego Clinic

    Francistown, Central District, Botswana

  • Morwa Clinic

    Mochudi, Central District, Botswana

  • Nyangabgwe Referral Hospital

    Francistown, Central District, Botswana

  • Palpye Primary Hospital

    Palapye, Central District, Botswana

  • Sefhare Primary Hospital

    Sefhare, Central District, Botswana

  • Sekgoma District Hospital

    Serowe, Botswana

  • Serowe Clinic

    Serowe, Botswana

  • Thamaga Primary Hospital

    Thamaga, Kweneng District, Botswana

  • Tutume Primary Hospital

    Tutume, Central District, Botswana

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