SURGICAL SITE INFECTION (SSI)
Clinical trials for SURGICAL SITE INFECTION (SSI) explained in plain language.
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One day of antibiotics may be enough after bone surgery
Disease control CompletedThis study looked at whether a one-day course of antibiotics is as good as a three-day course at preventing infections after femur or tibia fracture surgery with a metal rod (intramedullary nailing). Fifty-six adults were randomly assigned to receive either three or nine doses of…
Matched conditions: SURGICAL SITE INFECTION (SSI)
Phase: NA • Sponsor: Kathmandu University School of Medical Sciences • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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New antibiotic approach may cut infections after pancreatic surgery
Disease control CompletedThis study looked at 117 patients who had pancreatic surgery to see if changing the antibiotic given before surgery could reduce infections. The researchers compared an older antibiotic (cephalosporin) with a newer one (piperacillin/tazobactam) based on local bacteria patterns. T…
Matched conditions: SURGICAL SITE INFECTION (SSI)
Sponsor: Central Hospital, Nancy, France • Aim: Disease control
Last updated Jun 27, 2026 12:07 UTC
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Heart surgery patients get faster healing with own blood plasma
Disease control CompletedThis study tested whether applying a patient's own platelet-rich plasma (PRP) to the chest wound during heart surgery reduces infections and improves healing. 98 adults undergoing bypass surgery were randomly assigned to receive PRP or standard wound closure. Results showed that …
Matched conditions: SURGICAL SITE INFECTION (SSI)
Phase: NA • Sponsor: Shaheed Zulfiqar Ali Bhutto Medical University • Aim: Disease control
Last updated Jun 27, 2026 09:00 UTC
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Drain or rinse? study finds best way to prevent C-Section infections in obese moms
Prevention CompletedThis study tested two methods to prevent surgical site infection after cesarean section in 189 women with obesity (BMI 30 or higher). One group received a small drain under the skin, another had the wound rinsed with salt water, and a third had standard closure only. The goal was…
Matched conditions: SURGICAL SITE INFECTION (SSI)
Phase: NA • Sponsor: Ain Shams University • Aim: Prevention
Last updated Jun 27, 2026 12:08 UTC
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Wound infection breakthrough? local antibiotics may offer extra protection
Prevention CompletedThis study tested whether giving antibiotics directly into the surgical wound, in addition to standard IV antibiotics, reduces the chance of infection after elective surgeries like hernia repair or gallbladder removal. 284 adults took part, with one group receiving only IV cefazo…
Matched conditions: SURGICAL SITE INFECTION (SSI)
Phase: NA • Sponsor: Lahore General Hospital • Aim: Prevention
Last updated Jun 27, 2026 11:02 UTC
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New recovery plan may cut infections after emergency gut surgery
Symptom relief CompletedThis study tested whether a structured recovery plan (ERAS) could reduce infections and speed up recovery compared to standard care in 102 adults who had emergency abdominal surgery for a blocked or perforated bowel. Participants were randomly assigned to receive either the ERAS …
Matched conditions: SURGICAL SITE INFECTION (SSI)
Phase: NA • Sponsor: Recep Tayyip Erdogan Hospital Pakistan - Muzaffargarh • Aim: Symptom relief
Last updated Jun 27, 2026 14:00 UTC
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Stitch showdown: which wound closes better after stoma surgery?
Symptom relief CompletedThis study tested two ways to close the skin after reversing a temporary ileostomy (a surgically created opening in the belly). 252 adults were randomly assigned to either a straight-line closure or a purse-string closure that leaves a small gap for drainage. The goal was to see …
Matched conditions: SURGICAL SITE INFECTION (SSI)
Phase: NA • Sponsor: Hayat Abad Medical Complex, Peshawar • Aim: Symptom relief
Last updated Jun 27, 2026 12:32 UTC
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Foam vs gauze: which C-Section dressing heals scars better?
Symptom relief CompletedThis study compared two types of wound dressings—polyurethane foam and regular gauze—after cesarean delivery. 200 women were randomly assigned to one dressing type, and their scar appearance and infection rates were tracked for 6 months. The goal is to see if the foam dressing le…
Matched conditions: SURGICAL SITE INFECTION (SSI)
Phase: NA • Sponsor: Yewon Jung • Aim: Symptom relief
Last updated Jun 27, 2026 11:02 UTC
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Do you really need sterile gloves for wound care? small study investigates
Knowledge-focused CompletedThis pilot study looked at whether using clean non-sterile gloves for wound dressing after orthopedic surgery is as safe as using sterile gloves. Twenty-five patients were randomly assigned to one of two dressing techniques. The main goal was to compare infection rates within six…
Matched conditions: SURGICAL SITE INFECTION (SSI)
Phase: NA • Sponsor: Hamad Medical Corporation • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:08 UTC
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More metal, more misery: extra wires in thigh surgery linked to infections
Knowledge-focused CompletedThis study reviewed 148 patients who had thigh bone or hip replacement-related fracture surgery using metal wires (cerclage) to hold bone pieces together. Researchers found that using more wires was linked to a higher chance of deep infections and prolonged wound drainage. The fi…
Matched conditions: SURGICAL SITE INFECTION (SSI)
Sponsor: Istanbul University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:08 UTC
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Stitch by stitch: new study reveals best ways to close abdominal wounds
Knowledge-focused CompletedThis study looked at 217 adults who had abdominal surgery to see how different incision and stitching methods affect the chance of developing an incisional hernia (a bulge at the surgery site). Researchers compared a newer 'small-bite' stitching technique with the conventional me…
Matched conditions: SURGICAL SITE INFECTION (SSI)
Sponsor: Muğla Sıtkı Koçman University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC