One day of antibiotics may be enough after bone surgery
NCT ID NCT07554079
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at whether a one-day course of antibiotics is as good as a three-day course at preventing infections after femur or tibia fracture surgery with a metal rod (intramedullary nailing). Fifty-six adults were randomly assigned to receive either three or nine doses of cefuroxime after surgery. The goal was to see if shorter antibiotic use could safely reduce the risk of infection and antibiotic resistance.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- cefuroxime
- What this could lead to
- If a shorter antibiotic course works as well as a longer one, it could reduce antibiotic resistance and side effects for patients undergoing bone-nailing surgery.
- What could go wrong
- This is a small, single-center trial with only 56 participants, so results may not apply broadly. The study is also completed, so no new data is being collected.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for ANTIBIOTIC are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Dhulikhel Hospital, Kathmandu University Hospital
Dhulikhel, Bagmati, Nepal
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can robots perfectly align broken femurs?
- Can a nerve block beat painkillers for Broken-Bone positioning?
- A simple drain may slash wound infections after gynecologic cancer surgery
- Drone Warfare's hidden toll: new study tracks infection risk in combat wounds
- Vacuum bandage may shield ECMO patients from wound infections
- Wound injection may slash infection risk in emergency abdominal surgery