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Wound injection may slash infection risk in emergency abdominal surgery

NCT ID NCT07696819

Not yet recruiting Disease control Sponsor: Sylhet M.A.G.Osmani Medical College Source: ClinicalTrials.gov ↗

First seen Jul 10, 2026 · Last updated Jul 14, 2026 · Updated 2 times

Summary

This trial tests whether injecting the antibiotic levofloxacin directly into the wound edges during emergency abdominal surgery can prevent surgical site infections. Standard antibiotics given through the blood often don't reach high enough levels in the wound, especially when blood flow is poor. The study will enroll 90 adults undergoing emergency laparotomy for contaminated or infected abdominal conditions, and follow them for 30 days to check for infections.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
levofloxacin
What this could lead to
If it works, this simple, low-cost technique could significantly lower infection rates after emergency abdominal surgery, reducing complications and hospital stays.
What could go wrong
This is a small, single-center trial, so results may not apply broadly. Levofloxacin can cause side effects like tendon damage or nerve issues, and the injection itself might irritate the wound.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Surgical Wound Infection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SURGICAL SITE INFECTION (SSI)

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • Sylhet MAG Osmani Medical College

    Sylhet, 3100, Bangladesh

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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