New antibiotic dosing method could cut infections after heart surgery

NCT ID NCT07658378

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two ways of giving the antibiotic cefazolin during coronary artery bypass surgery to prevent wound infections. One group gets the drug as a steady drip (continuous infusion), the other as standard short injections. The trial will enroll 100 adults in Egypt and track how many develop a surgical site infection. If the continuous method works better, it could change how antibiotics are given during heart surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

cefazolin

What this could lead to

If continuous infusion works better, it could become a new standard to prevent infections after heart bypass surgery.

What could go wrong

This is a small, early-phase trial in one country, so results may not apply everywhere. The difference between the two methods may be small or not meaningful.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Surgical Wound Infection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

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