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Stitch by stitch: new study reveals best ways to close abdominal wounds

NCT ID NCT07340918

Knowledge-focused Sponsor: Muğla Sıtkı Koçman University Source: ClinicalTrials.gov ↗

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at 217 adults who had abdominal surgery to see how different incision and stitching methods affect the chance of developing an incisional hernia (a bulge at the surgery site). Researchers compared a newer 'small-bite' stitching technique with the conventional method and tracked patients for 12 months. The goal is to help surgeons choose techniques that reduce hernia risk and improve recovery.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

217 people

The number who actually took part.

Started

May 2021

Finished

Jul 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population consisted of adult patients undergoing midline abdominal surgery at a tertiary referral general surgery center in Muğla. Participants were recruited consecutively from routine clinical practice and included individuals treated for a wide range of benign and malignant abdominal conditions. Both elective and emergency procedures were represented, reflecting the full spectrum of surgical activity at the study center. All operations were performed by experienced general surgeons using standardized perioperative care protocols. The population therefore represents a real-world cohort of patients treated in a high-volume surgical unit, encompassing variability in surgical urgency, wound conditions, and case complexity. Patients were followed prospectively within the same institution using a standardized postoperative and long-term follow-up program.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adult patients (≥18 years of age) undergoing midline abdominal surgery * Patients undergoing elective or emergency laparotomy * Use of a midline abdominal incision with primary fascial closure * Application of either small-bite or conventional fascial closure technique * Availability of complete intraoperative data regarding incision and suture characteristics * Provision of written informed consent * Ability to participate in postoperative follow-up Exclusion Criteria: * Previous midline laparotomy or pre-existing incisional hernia * Relaparotomy for indications other than incisional hernia * Laparoscopic or minimally invasive procedures without midline fascial closure * Presence of a pre-existing abdominal wall defect at the incision site * Incomplete intraoperative data on closure technique or suture measurements * Loss to follow-up or inability to complete 12-month postoperative assessment

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Conditions

The condition(s) this trial relates to.

Incisional Hernia Postoperative Complications Surgical Wound Infection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Incisional hernia/prevention and control Surgical site infection (SSI)

Contacts and locations

Locations

  • Muğla Sıtkı Koçman Research and Training Hospital

    Muğla, 48000, Turkey (Türkiye)

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