SURGICAL SITE INFECTION (SSI)
Clinical trials for SURGICAL SITE INFECTION (SSI) explained in plain language.
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Heart surgery patients get faster healing with own blood plasma
Disease control CompletedThis study tested whether applying a patient's own platelet-rich plasma (PRP) to the chest wound during heart surgery reduces infections and improves healing. 98 adults undergoing bypass surgery were randomly assigned to receive PRP or standard wound closure. Results showed that …
Matched conditions: SURGICAL SITE INFECTION (SSI)
Phase: NA • Sponsor: Shaheed Zulfiqar Ali Bhutto Medical University • Aim: Disease control
Last updated Jun 22, 2026 12:05 UTC
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One day of antibiotics may be enough after bone surgery
Disease control CompletedThis study looked at whether a one-day course of antibiotics is as good as a three-day course at preventing infections after femur or tibia fracture surgery with a metal rod (intramedullary nailing). Fifty-six adults were randomly assigned to receive either three or nine doses of…
Matched conditions: SURGICAL SITE INFECTION (SSI)
Phase: NA • Sponsor: Kathmandu University School of Medical Sciences • Aim: Disease control
Last updated Jun 22, 2026 11:57 UTC
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Do you need sterile gloves for Post-Surgery wound care? new study investigates
Disease control CompletedThis pilot study looked at 25 adults who had knee surgery to see if using clean non-sterile gloves for wound dressing is as safe as sterile gloves. The main goal was to check for surgical site infections within 6 weeks after surgery. The study compared infection rates, hospital s…
Matched conditions: SURGICAL SITE INFECTION (SSI)
Phase: NA • Sponsor: Hamad Medical Corporation • Aim: Disease control
Last updated Jun 11, 2026 12:10 UTC
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Tailored antibiotics may cut infections after pancreatic surgery
Prevention CompletedThis study looked at 117 patients who had pancreatic surgery after having a bile duct stent. It compared infection rates before and after switching from one antibiotic to another (piperacillin/tazobactam). The goal was to see if matching the antibiotic to local bacteria patterns …
Matched conditions: SURGICAL SITE INFECTION (SSI)
Sponsor: Central Hospital, Nancy, France • Aim: Prevention
Last updated Jun 23, 2026 11:56 UTC
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Double-Duty antibiotics may slash surgery infections
Prevention CompletedThis study tested whether placing antibiotics directly into the surgical wound, in addition to standard IV antibiotics, could better prevent infections after surgery. 284 adults having elective surgeries like hernia repair or gallbladder removal took part. One group got the usual…
Matched conditions: SURGICAL SITE INFECTION (SSI)
Phase: NA • Sponsor: Lahore General Hospital • Aim: Prevention
Last updated Jun 22, 2026 12:03 UTC
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Drain or rinse? study finds best way to prevent C-Section infections in obese moms
Prevention CompletedThis study tested two methods to prevent surgical site infection after cesarean section in 189 women with obesity (BMI 30 or higher). One group received a small drain under the skin, another had the wound rinsed with salt water, and a third had standard closure only. The goal was…
Matched conditions: SURGICAL SITE INFECTION (SSI)
Phase: NA • Sponsor: Ain Shams University • Aim: Prevention
Last updated Jun 15, 2026 18:55 UTC
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New recovery plan may cut infections after emergency gut surgery
Symptom relief CompletedThis study tested whether a structured recovery plan (ERAS) could reduce infections and speed up recovery compared to standard care in 102 adults who had emergency abdominal surgery for a blocked or perforated bowel. Participants were randomly assigned to receive either the ERAS …
Matched conditions: SURGICAL SITE INFECTION (SSI)
Phase: NA • Sponsor: Recep Tayyip Erdogan Hospital Pakistan - Muzaffargarh • Aim: Symptom relief
Last updated Jun 23, 2026 12:09 UTC
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Stitch showdown: which wound closes better after stoma surgery?
Symptom relief CompletedThis study tested two ways to close the skin after reversing a temporary ileostomy (a surgically created opening in the belly). 252 adults were randomly assigned to either a straight-line closure or a purse-string closure that leaves a small gap for drainage. The goal was to see …
Matched conditions: SURGICAL SITE INFECTION (SSI)
Phase: NA • Sponsor: Hayat Abad Medical Complex, Peshawar • Aim: Symptom relief
Last updated Jun 16, 2026 12:55 UTC
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C-Section scar showdown: foam dressing beats gauze?
Symptom relief CompletedThis study tested whether a polyurethane foam dressing helps C-section scars heal better than a standard gauze dressing. 200 women who had a C-section were randomly assigned to one of the two dressings. Researchers checked scar appearance and infection rates over 6 months to see …
Matched conditions: SURGICAL SITE INFECTION (SSI)
Phase: NA • Sponsor: Yewon Jung • Aim: Symptom relief
Last updated Jun 12, 2026 12:05 UTC
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Stitch by stitch: new study reveals best ways to close abdominal wounds
Knowledge-focused CompletedThis study looked at 217 adults who had abdominal surgery to see how different incision and stitching methods affect the chance of developing an incisional hernia (a bulge at the surgery site). Researchers compared a newer 'small-bite' stitching technique with the conventional me…
Matched conditions: SURGICAL SITE INFECTION (SSI)
Sponsor: Muğla Sıtkı Koçman University • Aim: Knowledge-focused
Last updated Jun 12, 2026 12:05 UTC
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More metal, more misery: extra wires in thigh surgery linked to infections
Knowledge-focused CompletedThis study reviewed 148 patients who had thigh bone or hip replacement-related fracture surgery using metal wires (cerclage) to hold bone pieces together. Researchers found that using more wires was linked to a higher chance of deep infections and prolonged wound drainage. The fi…
Matched conditions: SURGICAL SITE INFECTION (SSI)
Sponsor: Istanbul University • Aim: Knowledge-focused
Last updated Jun 09, 2026 12:20 UTC