SURGICAL SITE INFECTION (SSI)

This study compares two common stitch materials—absorbable Vicryl and non-absorbable Prolene—for closing the abdominal wall after surgery. Researchers will track 156 patients in Pakistan for 6 months to see which suture leads to fewer hernias, infections, and less pain. The goal …

This study tests whether a new DNA test called Next Generation Sequencing (NGS) can help doctors better treat infections that happen after bone fracture surgery. About 250 adults with deep infections after fracture repair will be randomly assigned to get treatment based on standa…

This study tests whether applying vancomycin powder directly into the surgical wound during shunt placement can prevent infections in children with hydrocephalus. About 164 children will be randomly assigned to receive either standard care or standard care plus the powder. The go…

This study compares two ways of giving the antibiotic cefazolin during orthopedic surgery to see which better prevents surgical site infections. About 100 adults having major orthopedic surgery will be randomly assigned to receive the drug as a continuous drip or as standard inte…

This study tests a safety bundle—staff training, checklists, and audits—to prevent surgical site infections after emergency C-sections and open leg fracture repairs in Ethiopia. About 1,000 patients at public hospitals will be followed for 2 years to measure infection rates and d…

This study tests whether keeping blood sugar tightly controlled after brain surgery can prevent surgical site infections. About 572 adults having elective brain surgery will be randomly assigned to either intensive insulin therapy (continuous infusion) or standard care. The main …

This study looks at whether getting a surgical wound wet within 48 hours after skin surgery is safe compared to waiting 7 days. About 82 adults having minor skin procedures will be randomly assigned to early or delayed water exposure. Doctors will check for infections using a sta…