STAGE IV LUNG CANCER AJCC V8

This is a first-in-human study to find a safe dose of a new radioactive drug, Sn-117m-DTPA, for patients whose prostate, breast, or non-small cell lung cancer has spread to their bones. The drug is designed to deliver radiation directly to bone tumors while trying to spare the he…

This study is for people with advanced non-small cell lung cancer that has spread or come back and has gotten worse despite receiving standard chemotherapy and immunotherapy. It tests whether combining an experimental pill called SX-682 with an existing immunotherapy drug (atezol…

This study is testing whether the time of day a standard immunotherapy treatment is given affects how well it works for people with advanced solid tumors. Researchers want to see if a patient's internal body clock influences the treatment's effectiveness. About 160 participants w…

This study is testing whether combining a light-activated drug with immunotherapy can help control advanced non-small cell lung cancer that hasn't responded to standard treatments. The treatment involves injecting a drug that becomes active when exposed to a special laser light, …

This study is for people with advanced non-small cell lung cancer that has specific gene changes and has stopped responding to prior treatments. It will test whether two newer targeted drugs, given alone or together, can control the cancer better than standard options. The goal i…

This study aims to improve treatment for advanced non-small cell lung cancer by using blood tests to guide immunotherapy decisions. Researchers will track tumor DNA in the blood to determine when to continue, stop, or switch treatments. The goal is to develop personalized approac…

This study aims to see if a spinal fluid test can predict which patients with advanced lung cancer are likely to develop brain metastases. Researchers will collect spinal fluid and blood from 40 patients with stage III or IV non-small cell lung cancer, some with and some without …