STAGE IV LUNG CANCER AJCC V8

This study tested a combination of two immunotherapy drugs (durvalumab and tremelimumab) plus a targeted therapy (selumetinib) in 40 people with advanced non-small cell lung cancer that had returned or spread. The goal was to find the safest dose and see if the combo could shrink…

This early-phase trial is testing a combination of all-trans retinoic acid (ATRA), a substance made from vitamin A, and the immunotherapy drug atezolizumab in people with advanced non-small cell lung cancer that has spread or come back. The main goal is to find the safest dose an…

This early-phase trial tested two experimental drug combinations in 37 people with advanced EGFR-mutant lung cancer that no longer responded to the targeted therapy osimertinib. The goal was to find safe, tolerable doses of alisertib or sapanisertib when given together with osime…

This study tests a psychosocial program called Conquer Fear Support (CFS) for people with stage III or IV lung or gynecologic cancer who are experiencing fear of cancer progression. The program includes psychoeducation, attention training, worry management, and detached mindfulne…

This study tested a supportive care program for adults aged 60 and older with advanced lung cancer. The program combined physical therapy and relaxation exercises to help improve physical function and emotional wellbeing. Researchers measured how well participants stuck with the …

This study tested a new care model called BeWell360-CG, which provides health and wellness coaching to caregivers of people with advanced lung cancer. The goal was to see if the program could reduce caregiver burden and improve their quality of life. Fifty-five caregivers partici…

This completed study collected blood and tumor tissue from 64 patients with advanced cancers (like melanoma, breast, lung, and kidney cancer) to study genetic changes and treatment resistance. The samples are stored for future research, including genomic analysis. No new treatmen…