STAGE IV LUNG CANCER AJCC V8
Clinical trials for STAGE IV LUNG CANCER AJCC V8 explained in plain language.
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Brain cancer trial halted early: can Memory-Sparing radiation help when tumors return?
Disease control TerminatedThis phase III trial compared two radiation strategies for cancer that had spread to the brain and returned in new spots after initial radiosurgery. One group received focused radiation only to the new tumors, while the other received whole brain radiation that avoided the memory…
Matched conditions: STAGE IV LUNG CANCER AJCC V8
Phase: PHASE3 • Sponsor: NRG Oncology • Aim: Disease control
Last updated Jun 27, 2026 12:35 UTC
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Experimental triple therapy for advanced cancers shows early promise but trial halted
Disease control TerminatedThis early-phase trial tested the drug plinabulin combined with radiation and immunotherapy in 19 people with advanced cancers (like lung, bladder, or melanoma) that had stopped responding to standard immunotherapy. The goal was to see if the combination was safe and could shrink…
Matched conditions: STAGE IV LUNG CANCER AJCC V8
Phase: PHASE1, PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 12:26 UTC
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Personalized lung cancer trial halted early, but shows promise
Disease control TerminatedThis study tested whether matching specific targeted drugs to the genetic changes in a person's ALK-positive lung cancer could improve treatment. It included 10 adults with advanced non-small cell lung cancer that had already been treated. The trial was stopped early due to low e…
Matched conditions: STAGE IV LUNG CANCER AJCC V8
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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New drug combo targets brain metastases in advanced cancers
Disease control TerminatedThis study tested a combination of two drugs, bintrafusp alfa and pimasertib, in people whose cancer had spread to the brain. The goal was to find the safest dose and see if the treatment could slow or stop the cancer from growing. The trial was stopped early after enrolling only…
Matched conditions: STAGE IV LUNG CANCER AJCC V8
Phase: PHASE1, PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 11:02 UTC
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Promising cancer combo trial halted early
Disease control TerminatedThis study tested a new drug (BMS-986218) plus nivolumab and targeted radiation in people with advanced solid tumors that had spread. The goal was to see if this combination could help the immune system fight cancer better. Only 13 people took part before the study was stopped ea…
Matched conditions: STAGE IV LUNG CANCER AJCC V8
Phase: PHASE1, PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 09:09 UTC
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Experimental combo for tough lung cancer hits early snag
Disease control TerminatedThis early-phase trial tested a combination of two immunotherapy drugs (atezolizumab and varlilumab) plus targeted radiation in 16 people with advanced non-small cell lung cancer that had stopped responding to standard treatment. The goal was to see if the triple therapy was safe…
Matched conditions: STAGE IV LUNG CANCER AJCC V8
Phase: PHASE1 • Sponsor: Rutgers, The State University of New Jersey • Aim: Disease control
Last updated Jun 27, 2026 09:02 UTC
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Lung cancer combo trial halted early – what we know
Disease control TerminatedThis study tested whether adding bintrafusp alfa (an immunotherapy) to standard chemotherapy (docetaxel) helps people with advanced non-small cell lung cancer who have already tried other treatments. Only 10 people took part before the study was stopped early. The goal was to see…
Matched conditions: STAGE IV LUNG CANCER AJCC V8
Phase: PHASE2 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Jun 27, 2026 07:58 UTC
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Can meal timing protect your brain during cancer treatment?
Symptom relief TerminatedThis study tested a text-message-based diet program called Txt4fasting for people with breast or lung cancer that spread to the brain. The goal was to see if eating only during certain hours could reduce thinking and memory problems after radiation. Only 1 person enrolled before …
Matched conditions: STAGE IV LUNG CANCER AJCC V8
Phase: NA • Sponsor: Thomas Jefferson University • Aim: Symptom relief
Last updated Jun 27, 2026 09:10 UTC