STAGE IV LUNG CANCER AJCC V8
Clinical trials for STAGE IV LUNG CANCER AJCC V8 explained in plain language.
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New drug combo shows promise for Hard-to-Treat cancers, but study ends early
Disease control TerminatedThis early-phase study tested a drug called plinabulin combined with radiation and immunotherapy in 19 people with advanced cancers (like lung, bladder, or melanoma) that had stopped responding to standard immunotherapy. The goal was to see if the combo could shrink tumors or slo…
Matched conditions: STAGE IV LUNG CANCER AJCC V8
Phase: PHASE1, PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 17, 2026 02:19 UTC
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Promising lung cancer drug combo study halted early
Disease control TerminatedThis study tested several targeted drugs (ALK inhibitors) and chemotherapy in people with a specific type of advanced lung cancer called ALK-positive non-squamous non-small cell lung cancer. The goal was to see which treatment worked best based on the patient's tumor markers. Onl…
Matched conditions: STAGE IV LUNG CANCER AJCC V8
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 17, 2026 02:17 UTC
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New combo attack on stubborn lung cancer shows early promise but study cut short
Disease control TerminatedThis early-stage trial tested whether combining two immunotherapy drugs (atezolizumab and varlilumab) with radiation could help people whose advanced lung cancer had stopped responding to standard immunotherapy. Only 16 patients were enrolled before the study was ended early. The…
Matched conditions: STAGE IV LUNG CANCER AJCC V8
Phase: PHASE1 • Sponsor: Rutgers, The State University of New Jersey • Aim: Disease control
Last updated May 17, 2026 02:05 UTC
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Cancer brain metastasis drug combo trial halted early
Disease control TerminatedThis study tested two drugs, bintrafusp alfa and pimasertib, in people whose cancer had spread to the brain. The goal was to find the best dose and see if the combination could slow or stop tumor growth. The trial was stopped early after enrolling only 8 participants, so no clear…
Matched conditions: STAGE IV LUNG CANCER AJCC V8
Phase: PHASE1, PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 15, 2026 11:55 UTC
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Lung cancer study tests immunotherapy-chemo combo after standard treatments fail
Disease control TerminatedThis study tested whether adding the immunotherapy drug bintrafusp alfa to standard chemotherapy (docetaxel) helps people with advanced non-small cell lung cancer whose disease worsened after prior treatment with immunotherapy and chemotherapy. The trial planned to enroll 10 adul…
Matched conditions: STAGE IV LUNG CANCER AJCC V8
Phase: PHASE2 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated May 14, 2026 12:04 UTC
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Cancer combo trial halted early: what we learned
Disease control TerminatedThis early-stage trial tested a new immunotherapy drug (BMS-986218) combined with another immunotherapy (nivolumab) and precise radiation for people with advanced solid tumors that had spread. The goal was to see if the combination was safe and could shrink tumors. The study was …
Matched conditions: STAGE IV LUNG CANCER AJCC V8
Phase: PHASE1, PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 12, 2026 13:40 UTC
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Could meal timing protect your brain during cancer treatment?
Symptom relief TerminatedThis study tested a mobile app that helps people with brain metastases from breast or lung cancer follow a time-restricted eating plan. The goal was to see if changing when they eat could reduce memory and thinking problems after radiation therapy. Only one person enrolled before…
Matched conditions: STAGE IV LUNG CANCER AJCC V8
Phase: NA • Sponsor: Thomas Jefferson University • Aim: Symptom relief
Last updated May 13, 2026 16:03 UTC