New drug combo aims to shrink Hard-to-Treat lung tumors

NCT ID NCT07393555

First seen Feb 06, 2026 · Last updated May 14, 2026 · Updated 18 times

Summary

This study tests two drugs—sacituzumab govitecan and ivonescimab—alone or together in people with advanced non-small cell lung cancer that has certain gene changes (like EGFR or ALK) and has come back after prior treatment. The goal is to see if the combination works better than either drug alone at shrinking tumors or delaying cancer growth. About 117 participants will be enrolled.

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