New radioactive drug aims to hit bone tumors while sparing marrow

NCT ID NCT06982222

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This early-phase trial tests a radioactive drug called tin-117m-DTPA in 24 people with prostate, breast, or lung cancer that has spread to the bones. The drug is designed to deliver low-level radiation directly to bone tumors while being gentler on the bone marrow. Researchers will find the safest dose and watch for side effects and any signs that the tumors shrink or stop growing.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Tin-117m-DTPA (a radioactive compound that targets bone tumors)
What this could lead to
If it works, this could provide a new way to slow or shrink bone tumors while reducing damage to bone marrow.
What could go wrong
This is a very early, small Phase 1 trial focused on safety and dosing, not effectiveness. It may not work or may cause side effects like low blood counts.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

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