ST ELEVATION MYOCARDIAL INFARCTION

This study is testing whether a drug-coated balloon can be used instead of a permanent stent during emergency heart attack treatment. The balloon delivers medication to open the blocked artery and may reduce complications like blood clots or improper stent placement. Researchers …

This study tests whether dapagliflozin, a drug used for diabetes, can reduce heart muscle damage in people having a severe heart attack (STEMI). About 256 participants will receive either the drug or a placebo right before a procedure to open blocked arteries. The main goal is to…

This study tests if a newer, thinner stent (coated with a drug to prevent re-narrowing) plus a single, potent blood thinner (without aspirin) works as well as the standard two-drug therapy after a heart attack. The goal is to lower bleeding risk while still preventing future hear…

This study is testing a special balloon coated with a drug called sirolimus to treat blocked heart arteries. The balloon is inflated inside the artery to deliver the drug, which helps prevent the artery from narrowing again. About 1,118 adults with coronary artery disease will be…

This study tests an experimental drug called RTP-026 in people who have had a severe type of heart attack (STEMI). The goal is to see if the drug can safely reduce heart muscle damage when given shortly after emergency treatment to open blocked arteries. About 96 adults will part…

This study tests two methods used during emergency heart attack treatment: ischemic postconditioning (briefly pausing blood flow after opening the artery) and ultrasound-guided stent placement. The goal is to see if these approaches reduce death, heart failure, or the need for re…

This study aims to find out if using a detailed imaging technique called OCT leads to better long-term results than standard angiography when placing stents in people who have just had a major heart attack. It will involve 1500 participants who are having emergency stent placemen…

This study explores a new blood test that may detect active heart inflammation in people with sarcoidosis, a disease that can cause serious heart problems. Researchers will measure DNA fragments released from damaged heart cells in 120 participants, including healthy volunteers a…

This study will follow 20,000 people who had a heart attack and were discharged from the hospital early. Researchers want to see how well their medications are adjusted, track any major heart problems, and measure their quality of life over a year. The goal is to learn what works…

This study looks at people who had a major heart attack (STEMI) and have other blockages in their heart arteries. Doctors already fix the main blockage, but it's unclear which other blockages need stenting. The study uses CT scans and blood tests to see which blockages are likely…