Heart attack patients may ditch aspirin sooner with new stent
NCT ID NCT05785897
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study tests a new drug-coated stent and a blood thinner strategy without aspirin for people who have had a severe heart attack. The goal is to see if this approach lowers the risk of serious bleeding while still preventing future heart attacks, strokes, or the need for another procedure. About 350 participants will be randomly assigned to either the new stent plus a single blood thinner, or the standard stent plus two blood thinners (including aspirin) for 6-12 months.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
sirolimus-based nanocarrier eluting stent and P2Y12 inhibitor (ticagrelor or prasugrel) without aspirin
What this could lead to
If successful, this could offer a safer treatment option after a heart attack, reducing bleeding risk while still preventing future heart problems.
What could go wrong
This is a mid-sized trial, and the new approach may not be as effective at preventing stent clotting or heart attacks as the standard dual therapy. Bleeding risks, though potentially lower, still exist.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Geneva University Hospitals
RECRUITINGGeneva, Canton of Geneva, 1205, Switzerland
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Zurich University Hospital
RECRUITINGZurich, Switzerland
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••