Heart attack patients may ditch aspirin sooner with new stent
NCT ID NCT05785897
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study tests a new drug-coated stent and a blood thinner strategy without aspirin for people who have had a severe heart attack. The goal is to see if this approach lowers the risk of serious bleeding while still preventing future heart attacks, strokes, or the need for another procedure. About 350 participants will be randomly assigned to either the new stent plus a single blood thinner, or the standard stent plus two blood thinners (including aspirin) for 6-12 months.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- sirolimus-based nanocarrier eluting stent and P2Y12 inhibitor (ticagrelor or prasugrel) without aspirin
- What this could lead to
- If successful, this could offer a safer treatment option after a heart attack, reducing bleeding risk while still preventing future heart problems.
- What could go wrong
- This is a mid-sized trial, and the new approach may not be as effective at preventing stent clotting or heart attacks as the standard dual therapy. Bleeding risks, though potentially lower, still exist.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Geneva University Hospitals
RECRUITINGGeneva, Canton of Geneva, 1205, Switzerland
-
Zurich University Hospital
RECRUITINGZurich, Switzerland
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