ST ELEVATION MYOCARDIAL INFARCTION

This study compares a new approach using fewer stents and a drug-coated balloon to the standard method of placing stents in heart attack patients. About 1,272 participants will be randomly assigned to one of the two treatments. The goal is to see if the reduced-stent strategy low…

This study compares two ways to guide stent placement during a heart attack: standard angiography (X-ray) versus a more detailed imaging method called optical coherence tomography (OCT). The goal is to see if OCT leads to fewer future heart problems, like repeat blockages or hear…

This study tests two methods used during emergency heart attack treatment: ischemic postconditioning (briefly pausing blood flow after opening the artery) and ultrasound-guided stent placement. The goal is to see if these techniques reduce death, heart failure, or the need for an…

This study is testing a special balloon coated with the drug sirolimus to treat blocked heart arteries. The balloon is inflated inside the artery to push the blockage aside and release the drug, which helps prevent the artery from narrowing again. Researchers will follow over 1,1…

This study tests using a drug-coated balloon instead of a permanent stent to open blocked arteries during a heart attack. The balloon delivers medication to prevent re-blockage without leaving a metal implant. Researchers will track 300 participants to see if this approach is saf…

This study tests whether dapagliflozin, a diabetes drug, can limit heart muscle damage in people having a major heart attack (STEMI). Participants receive either the drug or a placebo for 7 days, and heart damage is measured with an MRI. The goal is to see if this drug can improv…

This study tests a new drug-coated stent and a blood thinner strategy without aspirin for people who have had a severe heart attack. The goal is to see if this approach lowers the risk of serious bleeding while still preventing future heart attacks, strokes, or the need for anoth…

This study looks at whether giving a PCSK9 inhibitor (alirocumab) soon after a heart attack can help save more heart muscle. About 160 adults having a specific type of heart attack will either get the drug or standard care. The main goal is to see if the drug improves heart muscl…

This study tests an experimental drug called RTP-026 in 96 adults who have had a severe type of heart attack (STEMI). Participants receive three short infusions of the drug or a placebo. The goal is to see if RTP-026 can reduce heart muscle damage, measured by blood markers. The …

This study explores a new blood test that looks for DNA fragments from damaged heart cells to detect active heart inflammation in people with sarcoidosis. Researchers will compare results from 120 participants, including healthy volunteers and those with known heart conditions. I…

This study follows 20,000 heart attack patients who are discharged early from the hospital after a minimally invasive procedure. Researchers want to see how well medications are adjusted, track major heart events, and measure quality of life over one year. No new treatment is giv…

This study tracks 1,650 people who had a first heart attack to see if men and women's hearts change shape and size differently during recovery. Using repeated heart scans (echocardiograms and MRIs), researchers aim to understand why women tend to have worse outcomes like heart fa…

This study uses a special type of MRI called diffusion tensor imaging to look at the structure of heart muscle in people with heart failure, recent heart attacks, or thickened heart walls. Researchers want to see how the heart's muscle fibers change over time, which may help expl…

This study looks at 320 people who had a severe heart attack (STEMI) and have blockages in other arteries besides the one that caused the attack. Researchers will use CT scans and blood tests to see which blockages are likely to cause future problems. The goal is to find out if o…