New balloon could open blocked heart arteries without a stent

NCT ID NCT07444957

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing a special balloon coated with the drug sirolimus to treat blocked heart arteries. The balloon is inflated inside the artery to push the blockage aside and release the drug, which helps prevent the artery from narrowing again. Researchers will follow over 1,100 patients for up to 3 years to see if this approach is safe and effective in everyday medical practice.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

sirolimus-coated balloon (a balloon catheter that delivers the drug sirolimus to open blocked arteries)

What this could lead to

If successful, this could provide a safe and effective way to treat coronary artery disease without leaving a permanent stent, potentially reducing long-term complications.

What could go wrong

This is an observational study, not a randomized trial, so results may be less definitive. The balloon may not work as well as stents in all patients, and there are risks like artery damage or re-narrowing.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

acute coronary syndrome acute myocardial infarction Angina, Stable coronary artery disorder intermediate coronary syndrome myocardial infarction Non-ST Elevated Myocardial Infarction silent myocardial infarction ST-elevation myocardial infarction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Hospital Álvaro Cunqueiro

    RECRUITING

    Vigo, Pontevedra, 36312, Spain