Heart attack drug combo may unclog arteries when standard methods fail
NCT ID NCT04573751
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This completed trial tested whether giving epinephrine and verapamil directly into the heart arteries could help restore blood flow in heart attack patients whose vessels remain blocked despite standard treatment. 104 adults with ST-elevation heart attacks were enrolled. The study compared standard therapy alone versus adding epinephrine, verapamil, or both.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
epinephrine and verapamil (given directly into the heart arteries)
What this could lead to
If it works, this could give doctors a new way to restore blood flow during a heart attack when standard treatments fail.
What could go wrong
This is a small, completed trial with 104 participants, so results may not apply to all patients. The drugs can affect blood pressure and heart rhythm.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Cardiology Research Institute, Tomsk NRMC
Tomsk, Tomsk Oblast, Russia