Heart attack drug combo may unclog arteries when standard methods fail
NCT ID NCT04573751
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This completed trial tested whether giving epinephrine and verapamil directly into the heart arteries could help restore blood flow in heart attack patients whose vessels remain blocked despite standard treatment. 104 adults with ST-elevation heart attacks were enrolled. The study compared standard therapy alone versus adding epinephrine, verapamil, or both.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- epinephrine and verapamil (given directly into the heart arteries)
- What this could lead to
- If it works, this could give doctors a new way to restore blood flow during a heart attack when standard treatments fail.
- What could go wrong
- This is a small, completed trial with 104 participants, so results may not apply to all patients. The drugs can affect blood pressure and heart rhythm.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Cardiology Research Institute, Tomsk NRMC
Tomsk, Tomsk Oblast, Russia
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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