SQUAMOUS CELL CARCINOMA OF THE HEAD AND NECK
Clinical trials for SQUAMOUS CELL CARCINOMA OF THE HEAD AND NECK explained in plain language.
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Immunotherapy drug may extend cancer-free time after head and neck cancer relapse
Disease control OngoingThis study tests whether the immunotherapy drug pembrolizumab, given after salvage surgery, can help keep head and neck cancer from returning in people whose cancer has come back locally. About 27 adults with confirmed squamous cell carcinoma of the head and neck are participatin…
Matched conditions: SQUAMOUS CELL CARCINOMA OF THE HEAD AND NECK
Phase: PHASE2 • Sponsor: Assuntina G. Sacco, MD • Aim: Disease control
Last updated May 17, 2026 03:28 UTC
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New combo therapy aims to extend life in Tough-to-Treat head and neck cancer
Disease control OngoingThis study tests whether adding the experimental drug monalizumab to the standard drug cetuximab helps people with advanced head and neck cancer live longer. The trial includes 370 adults whose cancer returned or spread after prior treatments, including immunotherapy. Participant…
Matched conditions: SQUAMOUS CELL CARCINOMA OF THE HEAD AND NECK
Phase: PHASE3 • Sponsor: AstraZeneca • Aim: Disease control
Last updated May 17, 2026 03:26 UTC
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New antibody combo shows promise in Hard-to-Treat cancers
Disease control OngoingThis trial tests a new antibody drug called acasunlimab (GEN1046) in people with advanced solid tumors that have stopped responding to standard treatments. The study has two parts: first, to find safe doses, and second, to see how well the drug works alone or combined with other …
Matched conditions: SQUAMOUS CELL CARCINOMA OF THE HEAD AND NECK
Phase: PHASE1, PHASE2 • Sponsor: Genmab • Aim: Disease control
Last updated May 15, 2026 11:55 UTC
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New drug cocktail shows promise against head and neck cancer
Disease control ENROLLING_BY_INVITATIONThis study tests whether combining two drugs, pertuzumab and lenvatinib, given before surgery can shrink advanced head and neck cancer tumors. About 30 adults with newly diagnosed, untreated cancer will receive the drug combination. The goal is to see how many patients have a com…
Matched conditions: SQUAMOUS CELL CARCINOMA OF THE HEAD AND NECK
Phase: PHASE2 • Sponsor: Zhejiang Provincial People's Hospital • Aim: Disease control
Last updated May 08, 2026 12:03 UTC
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Immunotherapy drug may keep High-Risk head and neck cancer at bay
Disease control OngoingThis study tests whether giving the immunotherapy drug pembrolizumab for one year after standard treatment can delay cancer recurrence in 100 people with high-risk head and neck cancer. Participants receive either pembrolizumab or a placebo, and researchers track how long they li…
Matched conditions: SQUAMOUS CELL CARCINOMA OF THE HEAD AND NECK
Phase: PHASE2 • Sponsor: University of Chicago • Aim: Disease control
Last updated Apr 30, 2026 15:48 UTC
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Can injecting immunotherapy directly into tumors help head and neck cancer patients?
Knowledge-focused OngoingThis early-phase study tests whether injecting the drug ipilimumab directly into head and neck tumors before surgery is safe and practical. Researchers will also study how the treatment affects the immune system. The study involves 18 adults with squamous cell carcinoma of the he…
Matched conditions: SQUAMOUS CELL CARCINOMA OF THE HEAD AND NECK
Phase: PHASE1 • Sponsor: Providence Health & Services • Aim: Knowledge-focused
Last updated May 14, 2026 12:05 UTC
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Scientists track Cancer's genetic shifts during therapy in new study
Knowledge-focused OngoingThis study looks at how certain cancers (head and neck, esophagus, and anal) change at the genetic and immune level when treated with chemotherapy or immunotherapy. About 39 adults with advanced cancer will provide blood and tumor samples before and during treatment. The goal is …
Matched conditions: SQUAMOUS CELL CARCINOMA OF THE HEAD AND NECK
Sponsor: University Health Network, Toronto • Aim: Knowledge-focused
Last updated May 13, 2026 15:59 UTC