MRI-Guided radiation boost shows promise in head and neck cancer trial

NCT ID NCT06880289

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests whether giving an extra dose of radiation to oxygen-poor (hypoxic) areas of head and neck tumors can improve treatment response. About 91 adults with advanced squamous cell cancer of the throat or voice box will receive standard chemo-radiation with or without the MRI-guided boost. The goal is to see if the boost leads to complete tumor disappearance.

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Conditions

The condition(s) this trial relates to.

head and neck squamous cell carcinoma hypopharynx squamous cell carcinoma laryngeal squamous cell carcinoma oropharynx squamous cell carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • "Regina Elena" National Cancer Institute

    Rome, Rome, 00144, Italy

  • IRCSS Regina Elena

    Roma, Roma, 00144, Italy