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Scientists hunt for blood markers to unmask hidden aggressive tumors

NCT ID NCT00568490

Recruiting now Knowledge-focused Sponsor: Stanford University Source: ClinicalTrials.gov ↗

First seen Jul 01, 2026 · Last updated Jul 02, 2026 · Updated 1 time

Summary

This study collects blood and tumor tissue samples from people with head and neck or lung cancers to find biological markers that indicate low oxygen levels within tumors. Low-oxygen tumors tend to be more aggressive and resistant to standard treatments like radiation and chemotherapy. By identifying these markers, researchers hope to develop better ways to predict tumor behavior and guide personalized treatment decisions.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could lead to a blood test that helps doctors identify aggressive, low-oxygen tumors and tailor treatment accordingly.
What could go wrong
This is an observational study focused on discovery, not treatment. The markers identified may not prove useful in practice, and further validation will be needed.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

head and neck cancer Head and Neck Neoplasms head and neck squamous cell carcinoma lip cancer lip neoplasm lung cancer lung neoplasm non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEAD AND NECK CANCER HEAD AND NECK CANCERS LIP CANCER LIP NEOPLASMS LUNG CANCER

Contacts and locations

Locations

  • Stanford University School of Medicine

    RECRUITING

    Stanford, California, 94305, United States

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