New hope for advanced cancers: JANX008 enters first human trials
NCT ID NCT05783622
First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 20 times
Summary
This early-phase trial tests a new drug called JANX008 in adults with advanced solid tumors (like lung, kidney, breast, or colorectal cancer) that have stopped responding to standard treatments. The main goals are to check safety, find the right dose, and see if the drug can shrink tumors. About 130 participants will receive the drug in a clinic setting.
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This is a summary of
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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City of Hope Medical Center
RECRUITINGDuarte, California, 91010, United States
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Henry Ford Health System
RECRUITINGDetroit, Michigan, 48202, United States
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Laura and Isaac Perlmutter Cancer Center NYU Langone Health
RECRUITINGNew York, New York, 10016, United States
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Ohio State University Hospital
RECRUITINGColumbus, Ohio, 43210, United States
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Rhode Island Hospital
RECRUITINGProvidence, Rhode Island, 02903, United States
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Sarah Cannon Research Institute
RECRUITINGNashville, Tennessee, 37203, United States
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The Christ Hospital Cancer Center
RECRUITINGCincinnati, Ohio, 45219, United States
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The University of Texas, MD Anderson Cancer Center
RECRUITINGHouston, Texas, 77030, United States
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UPMC Hillman Cancer Center
RECRUITINGPittsburgh, Pennsylvania, 15232, United States
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University of California San Diego Moores Cancer Center
RECRUITINGSan Diego, California, 92093, United States
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University of California, Davis Comprehensive Cancer Center
RECRUITINGSacramento, California, 95817, United States
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University of Chicago Medical Center
RECRUITINGChicago, Illinois, 60637, United States
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University of Michigan
RECRUITINGAnn Arbor, Michigan, 48109, United States
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University of North Carolina at Chapel Hill
RECRUITINGChapel Hill, North Carolina, 27599, United States
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University of Pennsylvania, Abramson Cancer Center
RECRUITINGPhiladelphia, Pennsylvania, 19104, United States
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University of Texas Southwestern Medical Center
RECRUITINGDallas, Texas, 75390, United States
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Washington University
RECRUITINGSt Louis, Missouri, 63110, United States
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Winship Cancer Institute, Emory University
RECRUITINGAtlanta, Georgia, 30308, United States
Conditions
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