SMALL CELL LUNG CANCER

This was a first-in-human study to find a safe dose of a new experimental cancer drug called SNB-101. The drug, a nanoparticle form of an existing chemotherapy, was given by IV to 21 patients with advanced solid tumors that had stopped responding to standard treatments. The main …

This large, completed Phase 3 trial tested whether adding a new drug called tiragolumab to a standard treatment could better control advanced small cell lung cancer. It involved 490 patients who had not yet received chemotherapy for their widespread disease. The study compared th…

This study tested if adding a new drug called trilaciclib to standard chemotherapy and immunotherapy could better control advanced small cell lung cancer. The main goal was to see if trilaciclib could protect patients' bone marrow and immune system from the harsh side effects of …

This study tested whether a new drug called trilaciclib could protect the bone marrow and immune system in people with advanced small cell lung cancer who were receiving chemotherapy (topotecan). The main goal was to see if trilaciclib could reduce severe drops in white blood cel…

This study looked back at the medical records of 45 patients to see if adding the drug durvalumab after they finished standard chemotherapy and radiation helped control their limited-stage small-cell lung cancer for a longer time. Researchers wanted to understand the real-world e…

This study tested a new combination of two drugs, NT-I7 and pembrolizumab, for people with advanced solid tumors that had returned or stopped responding to prior therapies. The main goals were to find a safe dose and see if the combination could shrink tumors in several hard-to-t…

This early-stage study tested the safety and best dose of a two-drug combination (tarlatamab plus AMG 404) for adults with small cell lung cancer that had worsened after standard chemotherapy. The main goal was to see how well patients tolerated the drugs and to check for any ser…

This study tested whether combining two drugs, anlotinib and penpulimab, could help control small cell lung cancer in patients whose initial platinum-based chemotherapy stopped working. It involved 65 participants who received both drugs to see if the combination could slow cance…

This study tested whether a special nursing program could help people with advanced small cell lung cancer better handle their treatment. 200 patients receiving standard chemo-immunotherapy were split into two groups: one received care from a dedicated team of nurses, doctors, an…

This study tested whether a special type of PET/CT scan could predict how well patients with a specific form of lung cancer would respond to standard treatment. Researchers scanned 33 patients before they started combined chemotherapy and radiation. They then followed the patient…

This study investigated whether a simple blood test could monitor lung cancer progression without needing repeated tumor biopsies. Researchers followed 200 lung cancer patients to see if genetic markers in their blood matched their tumor's genetic changes. The goal was to develop…