New drug combo shows promise in tough lung cancer
NCT ID NCT04885998
First seen Nov 01, 2025 · Last updated May 07, 2026 · Updated 24 times
Summary
This early-stage study tested a combination of two drugs, tarlatamab and AMG 404, in 23 adults with small cell lung cancer that had returned after standard treatment. The main goal was to check safety and find the best dose for future studies. This is not a cure, but aims to control the disease.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Chung Shan Medical University Hospital
Taichung, 40201, Taiwan
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Huntsman Cancer Institute
Salt Lake City, Utah, 84112, United States
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Medical University of South Carolina
Charleston, South Carolina, 29425, United States
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Medizinische Universitaet Innsbruck
Innsbruck, 6020, Austria
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National Cancer Center Hospital
Chuo-ku, Tokyo, 104-0045, Japan
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National Cancer Center Hospital East
Kashiwa-shi, Chiba, 277-8577, Japan
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National Cancer Centre Singapore
Singapore, 169610, Singapore
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National University Hospital
Singapore, 119074, Singapore
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Northwestern University, Robert H Lurie Comprehensive Cancer Center
Chicago, Illinois, 60611, United States
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Taipei Veterans General Hospital
Taipei, 11217, Taiwan
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Tennessee Oncology, PLLC
Nashville, Tennessee, 37203, United States
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Universitaetsklinikum Allgemeines Krankenhaus Wien
Vienna, 1090, Austria
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Universitair Ziekenhuis Antwerpen
Edegem, 2650, Belgium
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Universitair Ziekenhuis Leuven - Campus Gasthuisberg
Leuven, 3000, Belgium
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University Hospitals Cleveland Medical Center
Cleveland, Ohio, 44106, United States
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University of Kentucky
Lexington, Kentucky, 40536, United States
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Wake Forest Baptist Comprehensive Cancer Research Center
Winston-Salem, North Carolina, 27157, United States
Conditions
Explore the condition pages connected to this study.