New drug combo shows promise in Hard-to-Treat sarcomas
NCT ID NCT03449901
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a drug called ADI-PEG 20 combined with two chemotherapy drugs (gemcitabine and docetaxel) in 98 people with soft tissue sarcoma, osteosarcoma, Ewing's sarcoma, or small cell lung cancer. The goal was to see if the combination could slow cancer growth better than standard treatment. The approach targets cancers that lack a specific protein, making them more sensitive to the therapy.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Columbia University Medical Center
New York, New York, 10032, United States
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Sarcoma Oncology Center
Santa Monica, California, 90403, United States
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Stanford Medicine
Palo Alto, California, 94304, United States
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Washington University School of Medicine
St Louis, Missouri, 63110, United States