SEPTIC SHOCK
Clinical trials for SEPTIC SHOCK explained in plain language.
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Can a simple urine test prevent kidney failure in sepsis?
Disease control TerminatedThis study tested whether using a urine biomarker test (NephroCheck) to guide treatment could reduce kidney injury, dialysis, or death in sepsis patients. The trial planned to enroll many participants but was stopped early after only 19 people joined. The idea was to catch kidney…
Matched conditions: SEPTIC SHOCK
Phase: NA • Sponsor: BioMérieux • Aim: Disease control
Last updated Jun 27, 2026 09:11 UTC
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Timing of dialysis in septic shock: early vs. delayed – study halted early
Disease control TerminatedThis study looked at 500 adults with septic shock and severe acute kidney injury to see if starting dialysis early (within 12 hours) or waiting (48-60 hours) affected survival at 90 days. The trial was terminated early, so the results are not conclusive. The goal was to find the …
Matched conditions: SEPTIC SHOCK
Phase: PHASE3 • Sponsor: Centre Hospitalier Universitaire Dijon • Aim: Disease control
Last updated Jun 27, 2026 09:03 UTC
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Could a common sedative save lives in septic shock?
Disease control TerminatedThis study tested whether a sedative drug called dexmedetomidine could help restore blood pressure control in patients with severe septic shock that does not respond to standard treatments. The trial involved 32 adults in intensive care. The goal was to see if the drug could impr…
Matched conditions: SEPTIC SHOCK
Phase: PHASE3 • Sponsor: Centre Hospitalier Universitaire Dijon • Aim: Disease control
Last updated Jun 27, 2026 09:01 UTC
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Could a pill replace IV drips for septic shock? small trial halted early
Disease control TerminatedThis study tested whether the oral drug midodrine could help people with septic shock stop needing IV blood pressure support sooner. The trial planned to enroll many patients but was stopped early with only 10 participants. Because it was so small, we cannot draw firm conclusions…
Matched conditions: SEPTIC SHOCK
Phase: PHASE3 • Sponsor: University of Virginia • Aim: Disease control
Last updated Jun 27, 2026 07:51 UTC
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New sedation approach may help septic shock patients breathe on their own sooner
Symptom relief TerminatedThis study tested whether a gas sedative (isoflurane) could help patients with septic shock wake up and get off a breathing machine faster than standard IV sedation (midazolam). The goal was to reduce complications from long-term sedation and ventilation. Only one patient was enr…
Matched conditions: SEPTIC SHOCK
Phase: PHASE4 • Sponsor: University Hospital, Rouen • Aim: Symptom relief
Last updated Jun 27, 2026 09:03 UTC
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Blood pressure experiment in sepsis halted early – kidney protection still unclear
Knowledge-focused TerminatedThis study tested whether raising the blood pressure target from 65 mmHg to 85 mmHg in patients with septic shock could help prevent kidney injury. Researchers used a drug called norepinephrine to adjust blood pressure and monitored kidney function. The trial was stopped early an…
Matched conditions: SEPTIC SHOCK
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:06 UTC