SECONDARY ACUTE MYELOID LEUKEMIA
Clinical trials for SECONDARY ACUTE MYELOID LEUKEMIA explained in plain language.
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Scientists test Two-Pronged attack on tough blood cancers
Disease control CompletedThis early-stage study tested a combination of two drugs, veliparib and temozolomide, in adults with acute leukemias that had returned or were hard to treat. The main goal was to find the highest dose patients could safely tolerate. Researchers also wanted to see if the drug comb…
Matched conditions: SECONDARY ACUTE MYELOID LEUKEMIA
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Apr 01, 2026 14:43 UTC
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Experimental cell therapy tested for Tough-to-Treat blood cancers
Disease control CompletedThis study tested the safety of a new type of donor immune cell infusion for patients with advanced myelodysplastic syndrome (MDS) or secondary acute myeloid leukemia (AML) after their initial treatments stopped working. The goal was to see if these specially prepared cells from …
Matched conditions: SECONDARY ACUTE MYELOID LEUKEMIA
Phase: PHASE1, PHASE2 • Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Disease control
Last updated Mar 30, 2026 14:29 UTC
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New hope for frailest leukemia patients: gentler chemo combo tested
Disease control CompletedThis study tested a new, packaged form of two standard chemotherapy drugs (CPX-351) for adults newly diagnosed with a fast-growing blood cancer called AML. The patients were older or had other health problems, putting them at high risk of severe side effects from standard treatme…
Matched conditions: SECONDARY ACUTE MYELOID LEUKEMIA
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Mar 24, 2026 12:01 UTC
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Tailored treatment tested to boost survival for older leukemia patients
Disease control CompletedThis study tested a personalized approach to treat acute myeloid leukemia (AML) in adults aged 60 and older. Doctors assigned patients to either strong or milder chemotherapy based on their genetic risk and a detailed health assessment. The goal was to see if this tailored strate…
Matched conditions: SECONDARY ACUTE MYELOID LEUKEMIA
Phase: PHASE2 • Sponsor: University of Nebraska • Aim: Disease control
Last updated Mar 23, 2026 15:29 UTC
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Scientists test Triple-Threat attack on childhood cancer
Disease control CompletedThis study tested a new combination of three cancer drugs for children and young adults whose acute myeloid leukemia (AML) came back or did not respond to standard treatments. The main goal was to find the safest dose and understand the side effects. Researchers hoped this target…
Matched conditions: SECONDARY ACUTE MYELOID LEUKEMIA
Phase: PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Mar 23, 2026 15:16 UTC
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New hope for Tough-to-Treat leukemia: Three-Drug combo shows promise
Disease control CompletedThis study tested a new combination of three chemotherapy drugs (uproleselan, cladribine, and low-dose cytarabine) for adults with a specific type of acute myeloid leukemia (AML) that developed after treatment for another blood disorder. The main goals were to find the safest and…
Matched conditions: SECONDARY ACUTE MYELOID LEUKEMIA
Phase: PHASE1, PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Mar 17, 2026 13:09 UTC
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Scientists test new combo against aggressive blood cancers
Disease control CompletedThis study tested a combination of two drugs, ruxolitinib and CPX-351, for patients with advanced forms of certain blood cancers that had worsened. The main goals were to find the safest dose of the combination and to see how well it worked to control the cancer. The trial involv…
Matched conditions: SECONDARY ACUTE MYELOID LEUKEMIA
Phase: PHASE1, PHASE2 • Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Disease control
Last updated Mar 02, 2026 15:28 UTC
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Gentler transplant strategy tested for tough blood cancers
Disease control CompletedThis study tested a two-step, lower-intensity stem cell transplant for patients with high-risk blood cancers like leukemia and lymphoma. The goal was to use milder chemotherapy and radiation before the transplant to reduce side effects while still allowing the donor's immune cell…
Matched conditions: SECONDARY ACUTE MYELOID LEUKEMIA
Phase: PHASE2 • Sponsor: Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University • Aim: Disease control
Last updated Mar 02, 2026 15:26 UTC