New donor cell therapy shows promise for tough blood cancers

NCT ID NCT04620681

First seen Nov 01, 2025 · Last updated May 31, 2026 · Updated 32 times

Summary

This study tested an experimental treatment for people with myelodysplastic syndrome (MDS) or secondary acute myeloid leukemia (AML) whose first therapy stopped working. Nineteen adults received a special infusion of immune cells from a mismatched unrelated donor, designed to attack the cancer without permanently taking over the bone marrow. The main goal was to find a safe dose and see if the treatment could control the disease.

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Contacts and locations

Locations

  • Moffitt Cancer Center

    Tampa, Florida, 33612, United States

Conditions

Explore the condition pages connected to this study.