SARS COV-2

This Phase 2 trial tested the BNT162b2 mRNA vaccine in 960 healthy Chinese adults aged 18 to 85. Participants received two doses of either the vaccine or a placebo, 21 days apart. The main goal was to check safety and measure the immune response, specifically neutralizing antibod…

This study tested the safety and immune response of several Moderna mRNA vaccines for COVID-19, seasonal flu, RSV, and CMV in 308 healthy adults aged 18 to 75. Researchers monitored side effects and measured antibody levels after vaccination. The goal was to ensure the vaccines a…

This early-stage trial tested several experimental mRNA vaccines that aim to protect against both influenza and SARS-CoV-2 in a single injection. About 1,758 healthy adults aged 18 to under 80 took part. The main goals were to check safety and measure the immune response, with re…

This study tested two updated mRNA COVID-19 vaccines in over 1,800 children aged 6 months to under 6 years. The vaccines were given as a primary series or booster to see if they are safe and trigger a strong immune response against variants like Omicron. The goal is to protect yo…

This phase 2 study tested several new mRNA COVID-19 booster vaccines in 692 healthy adults who had already received a primary vaccine series. The goal was to compare the safety and immune response of these experimental boosters against a control vaccine. Participants received a s…

This study tested a new combination vaccine called mRNA-1083 that aims to protect against both flu and COVID-19 in a single shot. About 1,320 adults aged 18 to 64 took part. Researchers measured the immune response and checked for side effects to see if the combo vaccine works as…

This study tested a single shot that aims to protect against both COVID-19 and the flu. About 932 adults aged 50 to 64 received the experimental mRNA-1083 vaccine. Researchers checked for side effects and measured antibody levels one month after vaccination to see how well the va…

This completed Moderna trial tested the mRNA-1273 COVID-19 vaccine in over 4,300 healthy adolescents aged 12 to 17. The study looked at safety, side effects, and how well the vaccine works to prevent COVID-19. Participants received either the vaccine or a placebo, and some later …

This study tested a new DNA vaccine called GLS-5310 for COVID-19 in 171 healthy adults aged 19 to 85. The vaccine is given as a shot under the skin and aims to teach the body to fight the virus. Researchers checked for side effects and measured immune responses like T cells and a…

This study tested whether early treatment or preventive medication can help adults with COVID-19 feel better faster. 92 participants took part, and researchers tracked their symptoms daily for 28 days. The goal was to see if the treatments could reduce how long symptoms last and …

This study checked how well a new rapid test (LumiraDx) detects COVID-19 and flu A/B from a simple nose swab. Over 1,000 people with symptoms took part at clinics. The test aims to give fast results at the point of care, helping doctors tell these illnesses apart quickly.

This study checked how accurate two rapid tests (LumiraDx SARS-CoV-2 Ag Ultra and LumiraDx SARS-CoV-2 & Flu A/B) are at detecting COVID-19 and flu in people with symptoms. 716 participants provided nasal swabs at clinics. The results were compared to standard lab tests to measure…

This study tested a new saliva-based test for SARS-CoV-2 that gives results in less than an hour, without needing lab equipment. Researchers compared it to the standard PCR method using samples from 627 people, including healthcare workers and patients. The goal was to see if thi…

This study checked how well a new test called VitaSIRO solo™ detects COVID-19, flu, and RSV in people with respiratory symptoms. Over 1,200 participants provided nose and throat swabs. The test's accuracy was compared to standard lab methods.

This study tested 949 adults with COVID-19 symptoms to see how well saliva samples work compared to standard nasopharyngeal swabs. Each participant gave four samples: saliva for a rapid test and for PCR, and a nasal swab for both tests. The goal was to find out which combination …

This phase 3 trial tested a new COVID-19 vaccine called S-268019-b in nearly 10,000 adults. Participants received either the vaccine or a placebo to see if it could prevent COVID-19. The study looked at how many people got sick after vaccination and checked for safety and immune …

This study tested whether a budesonide nasal rinse (a steroid) could improve smell loss in 120 adults who still had trouble smelling 30 days after a mild COVID-19 infection. Participants used the rinse twice daily for 30 days, along with smell training. The goal was to see if mor…

This study looks at anonymous health records from California and Louisiana to see if the Pfizer-BioNTech COVID-19 vaccine helps prevent post-COVID conditions (long COVID). Researchers will also track who gets vaccinated. The study includes adults with a COVID-19 diagnosis between…

This completed study followed 829 people, including healthcare workers and a comparison group, over several years to understand how SARS-CoV-2 spreads and who gets sicker. Researchers collected swabs, blood, and saliva samples along with survey data. The goal was to identify risk…

This completed study from France compared over 1,500 ICU patients on ventilators to see if those with COVID-19 develop more lung infections than patients with influenza or no viral pneumonia. Researchers tracked cases of ventilator-associated pneumonia and tracheobronchitis. The …

This study examined how people with mild or no COVID-19 symptoms respond to the virus. Researchers measured immune markers in the blood of 57 adults who tested positive. The goal was to understand why some people clear the virus quickly while others develop severe illness.

This study tested whether measuring a protein called MxA in the blood can help doctors decide when to stop antiviral drugs in patients with flu or COVID-19. Researchers enrolled 86 adults and compared standard care to MxA-guided treatment. The goal was to see if the test could re…

This study looked at nearly 2,500 adults in the Olomouc region to find out how many had antibodies or cellular immunity against the SARS-CoV-2 virus, either from a past infection or from vaccination. Participants gave blood samples and answered a questionnaire. The goal was to un…

This study looked at whether nutritional status affects the risk of death in people aged 70 and older with COVID-19. Researchers followed 426 hospitalized patients, comparing those with and without the virus. The goal was to understand if poor nutrition makes COVID-19 more danger…

This completed study enrolled 760 adults who had tested positive for SARS-CoV-2 and recovered. Researchers collected blood and nasal samples to measure antibodies and immune cells. The goal was to understand how the body's immune system responds to natural infection, which could …

This study explored how changes in healthcare during the COVID-19 pandemic (2020-2021) impacted the quality of life and experiences of over 5,000 Dutch patients who had surgery or another medical procedure. Researchers first held focus groups to understand key themes, then create…

This study followed 187 people who had COVID-19 to see how their antibody levels changed over 24 months. Researchers took blood samples and, in some cases, nasal swabs to measure both general and neutralizing antibodies. They also looked at how the severity of the initial infecti…

This completed registry study collected data from 500 COVID-19 patients to learn how the virus affects kidney function. Researchers aimed to identify risk factors and track outcomes. The findings may help guide future treatment and care for kidney complications in COVID-19.

This completed study enrolled nearly 97,000 adults from long-running French health studies to track how many people had been infected with the coronavirus. Participants provided blood samples and answered questionnaires. The goal was to measure infection rates and understand what…

This study examined the immune systems of 120 COVID-19 patients who had trouble breathing. Researchers measured many immune markers in the blood to see if an overactive immune response causes lung damage. They also compared these markers to healthy people and looked for patterns …

This study tested over 1,000 healthcare workers for COVID-19 and tracked their antibody levels over time. The goal was to understand how the virus spreads among hospital staff and how the immune system responds. No treatment was given; the focus was on gathering information to gu…

This study looked at data from nearly 20 million people in California and Louisiana to see how well different versions of Pfizer's COVID-19 vaccine prevented severe illness, hospitalization, and death. Instead of enrolling new volunteers, researchers used existing health records …