SARS-COV-2
Clinical trials for SARS-COV-2 explained in plain language.
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Early trial tests new DNA-Based COVID-19 vaccine
⭐️ VACCINE ⭐️ CompletedThis study tested a new type of COVID-19 vaccine called GLS-5310, which uses DNA to teach the body's immune system to fight the virus. It involved 171 healthy adults and aimed to check if the vaccine was safe and if it triggered a protective immune response. The research was an e…
Matched conditions: SARS-COV-2
Phase: PHASE1, PHASE2 • Sponsor: GeneOne Life Science, Inc. • Aim: ⭐️ VACCINE ⭐️
Last updated Apr 01, 2026 14:41 UTC
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Two shots in one? moderna tests combo vaccine for seniors
⭐️ VACCINE ⭐️ CompletedThis study tested a single vaccine shot designed to protect against both COVID-19 and seasonal influenza. It involved 932 adults aged 50 to 65 to check the vaccine's safety and how well it triggers an immune response. Researchers compared different versions of the vaccine to see …
Matched conditions: SARS-COV-2
Phase: PHASE2 • Sponsor: ModernaTX, Inc. • Aim: ⭐️ VACCINE ⭐️
Last updated Apr 01, 2026 14:40 UTC
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One shot for two bugs? moderna tests combo vaccine
⭐️ VACCINE ⭐️ CompletedThis study tested a new mRNA vaccine designed to protect against both seasonal flu and COVID-19 in a single shot. It involved about 1,758 healthy adults and aimed to find the safest and most effective dose. The main goals were to check for side effects and see how well the vaccin…
Matched conditions: SARS-COV-2
Phase: PHASE1, PHASE2 • Sponsor: ModernaTX, Inc. • Aim: ⭐️ VACCINE ⭐️
Last updated Mar 31, 2026 12:12 UTC
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Chinese trial tests World's first major COVID-19 vaccine
⭐️ VACCINE ⭐️ CompletedThis study tested the safety and immune response of the Pfizer-BioNTech COVID-19 vaccine in 960 healthy Chinese adults. Participants received either two doses of the vaccine or a placebo shot, with researchers tracking their antibody levels and any side effects for about a year. …
Matched conditions: SARS-COV-2
Phase: PHASE2 • Sponsor: BioNTech SE • Aim: ⭐️ VACCINE ⭐️
Last updated Mar 31, 2026 12:12 UTC
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New COVID vaccine shows promise in major trial
⭐️ VACCINE ⭐️ CompletedThis large, completed study tested a new COVID-19 vaccine called S-268019-b from Shionogi. Nearly 10,000 people who had not been infected or vaccinated before participated. The main goal was to see if the vaccine could prevent people from getting sick with COVID-19 compared to a …
Matched conditions: SARS-COV-2
Phase: PHASE3 • Sponsor: Shionogi • Aim: ⭐️ VACCINE ⭐️
Last updated Mar 30, 2026 14:32 UTC
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Teen vaccine trial shows strong immune response against COVID-19
⭐️ VACCINE ⭐️ CompletedThis study tested the Moderna COVID-19 vaccine in over 4,300 healthy adolescents aged 12 to 17. The main goals were to check the vaccine's safety, side effects, and how well it worked to prevent COVID-19. Researchers compared the teens' immune responses to those seen in young adu…
Matched conditions: SARS-COV-2
Phase: PHASE2, PHASE3 • Sponsor: ModernaTX, Inc. • Aim: ⭐️ VACCINE ⭐️
Last updated Mar 30, 2026 14:28 UTC
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Moderna tests Next-Gen COVID shots for babies and toddlers
⭐️ VACCINE ⭐️ CompletedThis study tested updated Moderna COVID-19 vaccines designed to protect against newer virus variants in children from 6 months to under 6 years old. Researchers enrolled about 1,800 children to check how safe the vaccines are and how well they trigger an immune response. The stud…
Matched conditions: SARS-COV-2
Phase: PHASE3 • Sponsor: ModernaTX, Inc. • Aim: ⭐️ VACCINE ⭐️
Last updated Mar 27, 2026 12:39 UTC
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New COVID booster vaccines put to the test
⭐️ VACCINE ⭐️ CompletedThis study tested new COVID-19 booster vaccines in healthy adults who were already vaccinated. Researchers compared the safety and immune response of these new vaccines against a standard control vaccine. They also tested how different storage conditions might affect one of the v…
Matched conditions: SARS-COV-2
Phase: PHASE2 • Sponsor: GlaxoSmithKline • Aim: ⭐️ VACCINE ⭐️
Last updated Mar 23, 2026 15:17 UTC
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One shot for two bugs? moderna tests combo vaccine
⭐️ VACCINE ⭐️ CompletedThis study tested a new vaccine, mRNA-1083, designed to protect against both seasonal flu and COVID-19 with a single shot. It involved 1,320 healthy adults aged 18-65 to see how well their immune systems responded and to check for side effects. The goal was to see if this combina…
Matched conditions: SARS-COV-2
Phase: PHASE2 • Sponsor: ModernaTX, Inc. • Aim: ⭐️ VACCINE ⭐️
Last updated Mar 23, 2026 15:14 UTC
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Race to find better COVID-19 treatments for outpatients
Disease control CompletedThis study tested experimental drugs to treat COVID-19 early and prevent infection in people recently exposed. It involved 92 adults who either had mild-to-moderate COVID-19 symptoms or were healthy contacts of infected people. Researchers compared new treatments against standard…
Matched conditions: SARS-COV-2
Phase: PHASE2 • Sponsor: Henry M. Jackson Foundation for the Advancement of Military Medicine • Aim: Disease control
Last updated Apr 01, 2026 14:43 UTC
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Blood test could tell doctors when to stop antiviral drugs
Disease control CompletedThis small pilot study tested whether using a blood marker called MxA to guide when to stop antiviral treatment could improve outcomes for adults with flu or COVID-19. Researchers compared this new approach to standard care to see if it reduced the chance of the infection coming …
Matched conditions: SARS-COV-2
Phase: NA • Sponsor: Capital Medical University • Aim: Disease control
Last updated Mar 23, 2026 15:17 UTC
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New One-Swab test aims to quickly diagnose three major respiratory viruses
Diagnosis CompletedThis study tested a new diagnostic tool called the VitaSIRO solo™ assay to see how well it detects COVID-19, influenza (flu), and RSV in people with symptoms. Researchers enrolled over 1,200 participants who showed signs of a respiratory infection and collected nasal swabs from t…
Matched conditions: SARS-COV-2
Sponsor: Credo Diagnostics Biomedical Pte. Ltd. • Aim: Diagnosis
Last updated Apr 02, 2026 03:57 UTC
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Spit test for COVID? study compares ease and accuracy
Diagnosis CompletedThis study aimed to find out if saliva tests are as good as the standard deep nasal swab for detecting COVID-19. Researchers compared four methods: lab PCR tests and rapid antigen tests, each using both saliva and nasal samples. They enrolled 949 adults with COVID-like symptoms t…
Matched conditions: SARS-COV-2
Phase: NA • Sponsor: Center for Primary Care and Public Health (Unisante), University of Lausanne, Switzerland • Aim: Diagnosis
Last updated Mar 25, 2026 14:07 UTC
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Can a simple nasal spray bring back the scents COVID stole?
Symptom relief CompletedThis study tested whether a steroid nasal spray (budesonide) could help people regain their sense of smell after having COVID-19. It involved 120 adults who had lost their smell for at least 30 days after infection but had no other severe symptoms. The goal was to see if this com…
Matched conditions: SARS-COV-2
Phase: PHASE3 • Sponsor: Fondation Ophtalmologique Adolphe de Rothschild • Aim: Symptom relief
Last updated Mar 31, 2026 12:12 UTC
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Hospital workers tracked for COVID-19 to unlock immunity secrets
Knowledge-focused CompletedThis study aimed to understand how COVID-19 spread among healthcare workers and how their immune systems responded over time. Researchers followed over 1,000 hospital staff for up to five years, regularly testing them for the virus and for antibodies. The goal was to gather knowl…
Matched conditions: SARS-COV-2
Sponsor: University Medicine Greifswald • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:42 UTC
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Scientists track COVID's hidden toll on kidneys
Knowledge-focused CompletedThis study created a registry to understand how COVID-19 affects the kidneys. It tracked 500 patients with confirmed COVID-19 to see how often kidney injury occurred, who was most at risk, and what the outcomes were. The goal was to gather information to help guide future treatme…
Matched conditions: SARS-COV-2
Sponsor: University of Cologne • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:41 UTC
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Could a Senior's diet predict their COVID survival?
Knowledge-focused CompletedThis study looked at whether a person's nutritional status when they get sick affects their chance of surviving COVID-19. Researchers followed 426 people aged 70 and older who were hospitalized, comparing those with and without COVID-19. The goal was to see if being undernourishe…
Matched conditions: SARS-COV-2
Sponsor: Centre Hospitalier Universitaire Dijon • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:40 UTC
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Scientists map Body's defense after COVID-19 recovery
Knowledge-focused CompletedThis study aimed to understand how the body's immune system responds after recovering from a SARS-CoV-2 infection, which causes COVID-19. Researchers enrolled 760 adults who had previously tested positive for the virus and followed them for up to a year. By taking blood and nasal…
Matched conditions: SARS-COV-2
Sponsor: HIV Vaccine Trials Network • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:11 UTC
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Scientists map immune System's overreaction in severe COVID-19
Knowledge-focused CompletedThis study aimed to understand why some COVID-19 patients develop severe breathing problems. Researchers measured detailed immune system activity in 120 hospitalized patients with respiratory distress. They compared these patients to healthy volunteers to identify specific immune…
Matched conditions: SARS-COV-2
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:32 UTC
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Dutch study reveals Pandemic's hidden toll on surgery patients
Knowledge-focused CompletedThis study aimed to understand how pandemic-related healthcare changes affected the quality of life and care experiences of Dutch patients who needed surgery or medical procedures between 2020-2021. Researchers first interviewed patient groups to identify key themes, then created…
Matched conditions: SARS-COV-2
Sponsor: University Medical Center Groningen • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:32 UTC
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Pfizer scans millions of health records to see how well its COVID vaccines worked
Knowledge-focused CompletedThis study aimed to understand how well different versions of the Pfizer-BioNTech COVID-19 vaccine worked in the real world. Researchers analyzed existing health records from nearly 20 million people in California and Louisiana to see how well the vaccines prevented death, severe…
Matched conditions: SARS-COV-2
Sponsor: Pfizer • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:39 UTC
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Czech study tracks hidden COVID-19 immunity in thousands
Knowledge-focused CompletedThis study aimed to understand how many people in the Olomouc Region of the Czech Republic had developed immunity to COVID-19, either from past infection or vaccination. Researchers followed 2,484 adults who had participated in an earlier study, collecting their blood and saliva …
Matched conditions: SARS-COV-2
Phase: NA • Sponsor: The Institute of Molecular and Translational Medicine, Czech Republic • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:38 UTC
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Massive french study tracks COVID's hidden spread
Knowledge-focused CompletedThis study aimed to understand how many people in France had been infected with COVID-19 by testing blood samples from nearly 100,000 participants. It also looked at how social factors, health behaviors, and preventive measures affected infection rates. The goal was to gather kno…
Matched conditions: SARS-COV-2
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:16 UTC
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Scientists study why most people beat COVID-19 easily
Knowledge-focused CompletedThis study aimed to understand how the immune system fights off COVID-19 in people who have few or no symptoms. Researchers followed 57 adults with mild or asymptomatic infections to measure their immune responses and track how quickly they cleared the virus from their bodies. Th…
Matched conditions: SARS-COV-2
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Mar 13, 2026 15:05 UTC
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Scientists track COVID immunity for 24 months
Knowledge-focused CompletedThis study aimed to understand how long COVID-19 antibodies last in people who recovered from the virus. Researchers followed 187 patients for two years, measuring their antibody levels regularly. They wanted to see if protection differed between people who had mild versus severe…
Matched conditions: SARS-COV-2
Phase: NA • Sponsor: Centre Hospitalier Régional d'Orléans • Aim: Knowledge-focused
Last updated Mar 03, 2026 14:06 UTC