RADIOTHERAPY

This study tests whether a single, low dose of radiation to all visible tumors can help immunotherapy drugs work again in people with advanced esophageal cancer that stopped responding to standard treatment. About 32 adults will receive the radiation and continue their current im…

This study tests a new immunotherapy drug (QL1706) combined with chemotherapy and a special type of radiation (quad shot) in people with advanced non-small cell lung cancer that has not been treated before. The goal is to see if adding radiation improves tumor shrinkage and delay…

This study looks at people with stage IV non-small cell lung cancer that has spread to more than five places in the body. It tests whether giving high-dose radiation to the main lung tumor, along with standard drug therapy, can help them live longer or keep the cancer from growin…

This study looks at whether giving radiation therapy after surgery can help prevent a rare adrenal cancer from coming back in people at high risk. About 58 patients who had their tumor removed will be randomly assigned to either receive radiation or just be monitored. The goal is…

This study looks at whether giving radiotherapy after surgery for cancer that has spread to the spine helps patients live longer or have better quality of life. About 130 adults who had recent spinal surgery will be followed to compare those who get radiation and those who do not…

This early-phase study tests whether giving a precise, low-dose radiation to the center of a lung tumor can 'prime' the immune system before standard chemoradiation and immunotherapy. About 24 adults with stage III non-small cell lung cancer that cannot be removed by surgery will…

This study tests a new combination treatment for people with advanced solid tumors that have not responded to standard therapies. Participants will take PRaG-1 tablets (made from a natural fungus), receive targeted radiation, immune-boosting injections, and immunotherapy drugs. T…

This study tests if adding immunotherapy to standard treatment (radiation and chemotherapy before surgery) helps more people with high-risk rectal cancer achieve complete remission. It also compares a shorter course of radiation to a longer one. About 435 adults with locally adva…

This study tests whether a short course of radiation that spares the lymph nodes, followed by an immunotherapy drug (PD-1 inhibitor), can completely eliminate rectal cancer before surgery. It includes 44 adults with stage II-III rectal cancer. The goal is to see if this approach …

This study tests a combination of the chemotherapy drug TAS-102 and radiation therapy in people aged 65-85 with advanced esophageal cancer that has not spread widely. The goal is to find the best dose and see if the treatment helps patients live longer and controls the cancer. Ab…

This study looks at whether a supervised, moderate-intensity interval exercise program (like walking or cycling) can reduce inflammation, improve physical fitness, and boost quality of life in women with breast cancer who are undergoing radiotherapy. Forty women aged 20-65 with e…

This study looks at whether listening to calming music during the first radiation session can help cancer patients feel less anxious, stressed, and in pain. About 72 adults starting radiation will be split into two groups: one gets standard care, the other also gets a 15-20 minut…

This study tests whether using MRI scans to plan radiotherapy is better than using CT scans alone. Researchers will work with up to 150 cancer patients and 15 healthy volunteers to see if MRI can make treatment more precise and reduce side effects. The goal is to improve how doct…

This study tests a new device that tracks a patient's breathing movements during radiation therapy for cancers in the chest or upper abdomen. The goal is to see if the system can accurately guide the radiation beam without needing backup methods. About 20 adults will participate,…