RADIOTHERAPY

This study tests a new treatment for people with extensive-stage small cell lung cancer, a fast-growing cancer that has spread. It combines low-dose radiation to the chest with an immunotherapy drug (adebrelimab) and chemotherapy, followed by maintenance immunotherapy for up to t…

This study will follow 130 people who had surgery for cancer that spread to the spine. Half will get radiation after surgery, half will not. Researchers want to see if radiation helps keep the cancer from coming back and improves how long patients live. The goal is to help doctor…

This early-phase study tests whether giving a small, focused dose of radiation to the center of a lung tumor can safely 'prime' the immune system before standard chemoradiation and immunotherapy. About 24 adults with stage III non-small cell lung cancer that cannot be removed by …

This study looks at people with advanced non-small cell lung cancer that has spread to many places (more than five spots). It tests whether adding high-precision radiation to the main lung tumor, on top of standard drug therapy, helps them live longer and keeps the tumor from gro…

This phase 2 trial is testing a new approach for people with stage II-III rectal cancer. It combines short-course radiotherapy that spares the tumor-draining lymph nodes with a PD-1 inhibitor (a type of immunotherapy). The goal is to see if this combination can lead to a complete…

This study tests whether adding a special type of radiation (quad shot radiotherapy) to a new immunotherapy drug (QL1706) plus chemotherapy can better control advanced non-small cell lung cancer. About 104 people with stage IV lung cancer that has not been treated yet will take p…

This phase 2 trial tests a combination of PRaG-1 Cordycepin Tablets (from a fungus), radiation therapy, immune-boosting injections, and immunotherapy drugs in 65 adults with advanced solid tumors who have no standard treatment options. The goal is to see if this mix improves immu…

This study tests a chemotherapy drug (TAS-102) combined with radiation in people aged 65-85 with advanced esophageal cancer. The goal is to find the safest dose and see if the combination helps control the cancer and improves survival. About 45 participants will take part across …

This phase II trial tests whether a single low dose of radiation to all visible tumors can help immunotherapy work again in people with advanced esophageal cancer that has stopped responding to standard treatment. Thirty-two adults will receive the radiation and continue their or…

This study looks at whether giving radiation therapy after surgery can help prevent high-risk adrenocortical carcinoma from coming back. Fifty-eight patients who had their tumor completely removed will be randomly assigned to either receive radiation or just be monitored. The mai…

This study will test whether a robot named MIROKI can help children aged 4 to 18 feel less anxious during radiotherapy for cancer. Six children will have some sessions with the robot and some without, while their heart rate and behavior are monitored. The goal is to see if the ro…

This study tests whether moderate aerobic exercise, done during breast cancer radiotherapy, can reduce inflammation and improve physical fitness and quality of life. Forty women with early-stage breast cancer will either do supervised exercise sessions or receive usual care. Rese…

This study tests whether a short, personalized music listening session with a therapist can lower anxiety, stress, and pain in cancer patients starting radiation therapy. 72 adults will be randomly assigned to receive music therapy during their first radiation session or standard…

This study will observe 200 cancer patients who are already receiving immunotherapy (immune checkpoint inhibitors) along with radiotherapy. Researchers want to see how long the cancer stays under control and how patients fare overall, in everyday clinical practice rather than a s…

This study tests whether using MRI scans to plan radiotherapy is better than using CT scans alone. Researchers will work with up to 150 cancer patients and 15 healthy volunteers to see if MRI can make treatment more precise and reduce side effects. The goal is to improve how tumo…