Mushroom-Derived compound joins forces with radiation and immunotherapy to fight advanced cancers

NCT ID NCT07267234

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This phase 2 trial tests a combination of PRaG-1 Cordycepin Tablets (from a fungus), radiation therapy, immune-boosting injections, and immunotherapy drugs in 65 adults with advanced solid tumors who have no standard treatment options. The goal is to see if this mix improves immune function and slows tumor growth. All participants receive the same treatment; there is no placebo group.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

PRaG-1 Cordycepin Tablets (a natural compound from Cordyceps fungus) combined with radiation therapy, GM-CSF injections, and PD-1/PD-L1 inhibitors

What this could lead to

If this works, it could offer a new treatment option for people with advanced solid tumors who have run out of standard options.

What could go wrong

This is a small, early-phase trial with only 65 participants and no comparison group, so results may not apply broadly. The combination therapy may cause side effects or fail to slow tumor growth.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cancer lymphopenia neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

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