PSYCHOTIC DISORDERS

This study tests a comprehensive health program for 644 people with psychotic disorders. The program provides regular check-ups, motivational tools, and support from a team of health professionals to improve heart health and quality of life. Researchers will compare the program t…

This study tests a treatment called Magnetic Seizure Therapy (MST) for people with psychotic disorders like schizophrenia. The therapy uses magnetic pulses to trigger a controlled seizure in the brain, aiming to improve symptoms when added to regular medication. About 50 adults a…

This study tests whether using a person's genetic information to choose psychiatric medications leads to better recovery than standard prescribing. About 2,500 adults with depression, anxiety, or psychotic disorders will receive either genetically tailored treatment or usual care…

This study tests a brief group therapy called Resilience Training for Teens. It aims to prevent serious mental illness in high school students aged 14-19 who have mild symptoms of depression, anxiety, or unusual feelings. About 70 teens will participate to see if the training hel…

This study tests a program called Resilience Training for college students who have mild psychotic experiences, like unusual thoughts or perceptions. The goal is to see if this training can prevent them from developing a serious mental illness. About 192 students aged 18-30 will …

This study is testing whether a 24-week supervised exercise program (a mix of aerobic, strength, and flexibility exercises) can improve physical fitness, mood, and quality of life in 44 adults with psychosis who are already on long-acting injectable medication. Participants will …

This study is testing whether a yoga-based group program can help people with schizophrenia spectrum disorders feel better and manage their symptoms. Researchers are comparing yoga to simple strength and flexibility exercises and to standard care alone. The goal is to see if the …

This study tests a 9-week education program for families of young adults (ages 17-27) with psychosis. The program teaches practical skills to reduce the burden on caregivers and help keep patients stable in the community. Researchers will measure changes in family stress, patient…

This study tests a short, two-session program for young adults with psychosis who have had negative healthcare experiences. The goal is to help them feel more connected to their treatment and improve their recovery. Researchers will compare outcomes between those with and without…

This study tests whether cognitive behavioral therapy for chronic pain (CBT-CP) can help veterans with serious mental illness (like schizophrenia or bipolar disorder) who also have chronic low back pain. Researchers will measure changes in pain interference, quality of life, and …

This study tests whether a smartphone app called Kiso Mind is acceptable and helpful for people with schizophrenia or schizoaffective disorder. About 60 participants will either use the app plus their usual care, or just usual care, for 12 weeks. The goal is to see if the app is …

This study tests a virtual reality program designed to help people with psychosis improve their thinking and social skills. About 52 adults aged 18-60 with stable psychosis will use the program and do homework. The goal is to see if it's practical and helpful for daily life.

This study looks at whether cognitive remediation—a type of brain training with coaching—can improve thinking skills, daily function, and behavior in people staying in a forensic mental health unit. About 30 adults with conditions like psychosis, ADHD, or substance use will take …

This study looks at 200 children and teens (ages 7-20) who have had a psychotic episode, such as in schizophrenia. Researchers will use interviews, brain scans, and genetic tests to group participants by their symptoms. The goal is to see if these groups can predict which antipsy…

This study aims to understand why Black Americans often report higher levels of paranoia than White Americans. Researchers will have 480 Black American participants complete tasks that may be stressful related to race, then measure their feelings of paranoia. The goal is to impro…