PSYCHOTIC DISORDERS
Clinical trials for PSYCHOTIC DISORDERS explained in plain language.
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Step-by-step therapy may curb psychosis risk in teens and young adults
Disease control CompletedThis study tested a staged treatment approach for 342 young people aged 12-25 who are at ultra high risk of developing psychosis. Participants received different combinations of therapy, case management, and medication over time. The goal was to see if a stepwise plan could impro…
Matched conditions: PSYCHOTIC DISORDERS
Phase: PHASE3 • Sponsor: Orygen • Aim: Disease control
Last updated May 17, 2026 06:22 UTC
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VR headset could sharpen thinking in depression and psychosis
Symptom relief CompletedThis study tested whether a 4-week virtual reality (VR) training program could improve thinking skills and daily functioning in 62 adults with stable mood disorders (like depression or bipolar disorder) or psychosis spectrum disorders (like schizophrenia). Participants used VR to…
Matched conditions: PSYCHOTIC DISORDERS
Phase: NA • Sponsor: Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital • Aim: Symptom relief
Last updated May 17, 2026 06:44 UTC
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Turmeric extract shows promise for schizophrenia symptoms in small trial
Symptom relief CompletedThis study tested whether adding curcumin (the active compound in turmeric) to the standard medication risperidone could improve quality of life and reduce inflammation in people with schizophrenia. Forty-four men took either risperidone alone or risperidone plus curcumin for 8 w…
Matched conditions: PSYCHOTIC DISORDERS
Phase: NA • Sponsor: Rinvil Renaldi • Aim: Symptom relief
Last updated May 15, 2026 11:54 UTC
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New hope for veterans with chronic pain and mental illness: therapy shows promise
Knowledge-focused CompletedThis study looked at whether a type of talk therapy called Cognitive Behavioral Therapy for Chronic Pain (CBT-CP) works for veterans who also have serious mental illnesses like schizophrenia or bipolar disorder. 47 veterans took part to see if the therapy was acceptable and helpf…
Matched conditions: PSYCHOTIC DISORDERS
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Knowledge-focused
Last updated May 17, 2026 06:47 UTC
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Brain study seeks clues in early psychosis
Knowledge-focused CompletedThis study looked at how young adults aged 18-30 with early psychosis process information from their surroundings, compared to those without a psychiatric diagnosis. Participants completed computer-based tasks and cognitive training to measure changes in attention and decision-ma…
Matched conditions: PSYCHOTIC DISORDERS
Phase: EARLY_PHASE1 • Sponsor: University of Minnesota • Aim: Knowledge-focused
Last updated May 17, 2026 06:43 UTC
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Can peers help teens with psychosis quit drugs? new study says maybe.
Knowledge-focused CompletedThis study tested a program called PAS-EPP, where trained peer supporters help young people with early psychosis reduce or stop using alcohol and drugs. About 113 participants from coordinated specialty care teams took part. The goal was to see if the program is practical and acc…
Matched conditions: PSYCHOTIC DISORDERS
Phase: NA • Sponsor: University of Texas at Austin • Aim: Knowledge-focused
Last updated May 15, 2026 11:54 UTC
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Phone app trains Self-Awareness to boost daily life in psychosis
Knowledge-focused CompletedThis study tested a new training program called iTEST for 69 adults with schizophrenia or schizoaffective disorder. The program uses daily mobile tasks, like guessing emotions from faces or remembering words, to help people improve how accurately they judge their own performance.…
Matched conditions: PSYCHOTIC DISORDERS
Phase: NA • Sponsor: University of California, San Diego • Aim: Knowledge-focused
Last updated Apr 24, 2026 16:18 UTC