PSORIATIC ARTHRITIS

This study tested a higher dose (10 mg/kg every 8 weeks) of the drug TA-650 in 51 adults with psoriasis whose symptoms had returned after initially responding to the standard dose of Remicade. The goal was to see if the higher dose could again improve skin symptoms. The study mea…

This study tested two injectable drugs, secukinumab and ustekinumab, in 119 adults with active psoriatic arthritis who had not responded to or could not tolerate TNFα inhibitors. The main goal was to see which drug better improved physical function over 28 weeks. Both drugs aim t…

This study tested a new medicine, bimekizumab, for people with active psoriatic arthritis, a condition causing joint pain and swelling. About 852 adults took part, comparing bimekizumab to a placebo and an existing drug (adalimumab). The main goal was to see if bimekizumab could …

This study followed 76 adults who had shoulder replacement surgery with the MIRAI prosthesis to see how well their shoulder function and the implant itself held up over 5 years. Researchers measured pain, movement, and disability using standard shoulder scores, and also checked f…

This study tested a daily pill called upadacitinib in 1,705 adults with active psoriatic arthritis who had not gotten enough relief from standard non-biologic drugs. The goal was to see if it reduced joint pain and swelling better than a placebo or an injected biologic (adalimuma…

This study looked at whether adding a weight-loss drug (tirzepatide) to a standard psoriatic arthritis medicine (ixekizumab) helps people with both conditions. 279 adults with active psoriatic arthritis who were overweight or had obesity took part. The goal was to see if the comb…

This study tested a drug called bimekizumab in 435 adults with moderate to severe plaque psoriasis, a skin condition causing red, scaly patches. Participants received either bimekizumab or a placebo for 16 weeks to see if the drug could clear most of the skin symptoms. The goal w…

This study tested whether adding golimumab (a biologic drug) to standard methotrexate works better than methotrexate alone for people with very early psoriatic arthritis. 84 adults with active disease participated. The main goal was to see if the combination reduced joint swellin…

This study looked at how well the drug tofacitinib works for people with psoriatic arthritis in everyday medical practice. 116 adults with moderate to severe disease were observed for 12 months after starting the medication. The goal was to see if the drug could reduce disease ac…

This study tested a new drug called bimekizumab in 567 adults with moderate to severe plaque psoriasis. Participants received either bimekizumab, a placebo, or another active drug. The main goal was to see if bimekizumab could significantly clear skin symptoms by week 16. Results…

This study looked at over 2,300 adults with moderate to severe plaque psoriasis or psoriatic arthritis who were prescribed Skyrizi (risankizumab) by their doctor. Researchers wanted to see how safe the drug is and how well it controls symptoms over 52 weeks. Participants received…

This study tested a daily medication called upadacitinib in 642 adults with active psoriatic arthritis who had not gotten enough relief from prior biologic drugs. The goal was to see if the drug could reduce joint pain and swelling better than a placebo. Results showed that upada…

This study looked at 192 adults with newly diagnosed moderate to severe psoriatic arthritis to see if starting stronger treatment early works better than the usual step-up approach. Participants were split into three groups: standard care, early combination drugs, or early biolog…

This study tested a drug called bimekizumab in 400 adults with active psoriatic arthritis who had not responded well to standard TNF-blocking treatments. The goal was to see if bimekizumab could reduce joint pain and swelling better than a placebo. Results focused on at least 50%…

This study tested whether people with rheumatoid, psoriatic, or spine arthritis could safely switch from receiving infliximab through an IV at the hospital to giving themselves a simple injection at home every two weeks. 22 adults who were already stable on IV infliximab were off…

This study looked at whether switching from a lower to a higher concentration of adalimumab (AVT-02) reduces injection site pain and improves treatment adherence. It involved 324 adults with conditions like Crohn's disease, rheumatoid arthritis, or psoriasis. Researchers measured…

This study tested whether structured telemedicine visits that encourage lifestyle changes can improve quality of life and reduce disease activity in people with psoriatic arthritis. 101 adults with active symptoms took part. Researchers measured satisfaction, disease impact, and …

This study looked at whether intermittent fasting (eating only during certain hours) can reduce disease severity and improve quality of life for people with psoriasis and psoriatic arthritis. Sixty overweight adults were randomly assigned to either follow an intermittent fasting …

This study tested if a non-invasive ultrasound device can reduce inflammation in people with psoriatic arthritis, rheumatoid arthritis, or ankylosing spondylitis. Sixteen participants each received four ultrasound sessions, with one session being a placebo. The main goal was to m…

This study looked at 70 adults with psoriatic arthritis to compare two types of drugs—upadacitinib and IL-17 inhibitors—in everyday medical practice. Researchers tracked joint and skin symptoms over 24 weeks to see which treatment worked better. The goal is to help doctors and pa…

This study looked at fatigue in 33 adults with psoriatic arthritis or psoriasis. Researchers used questionnaires to compare tiredness levels and see if they relate to disease severity or type of treatment. The goal was to better understand fatigue, a common but poorly understood …

This study involved 37 adults with psoriasis or psoriatic arthritis who were starting or switching treatments. Researchers worked with patients and doctors to create a decision aid—a simple tool to help people discuss their options and make shared choices. The goal was to improve…

This study looked at the safety of the drug abatacept in over 140,000 people with rheumatoid arthritis or psoriatic arthritis in Sweden. Researchers tracked how many people developed different types of cancer while taking abatacept or other arthritis medications. The goal was to …

This study followed 127 adults with moderate to severe plaque psoriasis, psoriatic arthritis, ankylosing spondylitis, or non-radiographic axial spondyloarthritis for 2 years to see how long they stayed on secukinumab treatment and how their quality of life changed. Researchers co…