PSORIATIC ARTHRITIS

This study looked at switching patients with rheumatoid arthritis, spondyloarthritis, or psoriatic arthritis from receiving their infliximab medication through an intravenous (IV) infusion at a clinic to giving themselves a subcutaneous (SC) injection at home. The main goal was t…

This study tested an investigational drug called bimekizumab in adults with moderate to severe plaque psoriasis. It was a large, late-stage trial comparing the drug to a placebo to see how well it cleared skin and reduced symptoms like itch and pain. The main goal was to see if p…

This study followed 127 adults for two years to see how well they stayed on a prescribed drug called secukinumab, which treats several related inflammatory conditions. Researchers tracked whether patients continued treatment and measured changes in their symptoms, pain, and quali…

This study compared two types of arthritis medications in real-world patients to see which works better for controlling joint pain and skin symptoms. Researchers followed 70 adults with psoriatic arthritis for 24 weeks, comparing upadacitinib pills against IL-17 inhibitor injecti…

This study observed how well the existing drug tofacitinib worked for people with psoriatic arthritis in their normal, everyday treatment. It followed 116 patients for a year to see if the drug could reduce their disease activity, help them achieve remission, and improve their qu…

This study tested whether a non-invasive, focused ultrasound treatment could reduce harmful inflammation in people with inflammatory arthritis. Sixteen participants, including healthy volunteers and people with conditions like rheumatoid arthritis, received several ultrasound ses…

This study followed 76 patients for five years after they received a new type of total shoulder replacement. The goal was to see how well the new implant system worked to relieve pain, restore shoulder movement, and remain stable over time. Researchers measured patients' function…

This study tested whether a new injectable drug called bimekizumab could safely reduce the joint pain, swelling, and skin symptoms of psoriatic arthritis. It involved 852 adults and compared bimekizumab against a placebo (dummy treatment) and an existing drug, adalimumab. The mai…

This study compared the effectiveness and safety of two injectable biologic drugs, secukinumab and ustekinumab, in adults with active psoriatic arthritis. It focused on patients whose symptoms were not adequately controlled by a common first-line biologic treatment. Over 28 weeks…

This study tested whether a daily pill called upadacitinib could help people with active psoriatic arthritis who didn't get enough relief from previous biologic injections. Researchers enrolled 642 participants and compared two doses of the pill against a placebo over 24 weeks, t…

This study tested if a combination of two drugs, golimumab and methotrexate, is better at controlling disease activity in people with very early psoriatic arthritis than methotrexate alone. It involved 84 adults who had not yet tried standard arthritis medications. The goal was t…

This study compared three treatment approaches for people newly diagnosed with moderate to severe psoriatic arthritis. Researchers tested whether starting with stronger combination medications or biologic drugs works better than the standard approach of starting with one medicati…

This study tested whether doubling the dose of the drug TA-650 could help patients with moderate-to-severe psoriasis who initially responded to a standard dose but later saw their symptoms return. The trial involved 51 adults with different forms of psoriasis, including plaque ps…

This study tested whether an injectable drug called bimekizumab could help people with active psoriatic arthritis who hadn't gotten enough relief from their previous standard treatments. It involved 400 participants and compared the drug against a placebo (inactive shot) to see i…

This study tested an investigational drug called bimekizumab for adults with moderate to severe plaque psoriasis. It compared bimekizumab against a placebo and an existing treatment to see how well it cleared skin plaques and reduced symptoms like itch and pain. The main goal was…

This study tested if a new daily pill called upadacitinib could better control the joint pain, swelling, and skin symptoms of psoriatic arthritis. It was compared against a placebo (a dummy pill) and an existing injectable treatment, adalimumab (Humira). Over 1,700 adults who had…

This study looked at whether switching patients to a higher concentration version of the drug adalimumab (brand name SIMLANDI™) causes less injection site pain than the standard version. It involved 324 adults in Canada who were already using adalimumab for conditions like Crohn'…

This study tested whether regular video visits with trained clinicians could help people with psoriatic arthritis make lifestyle changes to improve their quality of life. Over 100 participants with active symptoms used a program called PsOWell, where clinicians helped them set pe…

This study aimed to understand and compare the experience of fatigue in people with psoriatic arthritis and those with skin psoriasis. Researchers enrolled 33 adult patients to complete questionnaires about their fatigue levels and quality of life. The goal was to see how fatigue…

This study tracked over 140,000 people in Sweden with rheumatoid or psoriatic arthritis to see if the drug abatacept affects their risk of developing cancer. Researchers compared cancer rates in people taking abatacept to those taking other standard arthritis medications. The goa…

This study aimed to create and test a decision-making tool for patients with psoriasis or psoriatic arthritis. The tool was designed to help patients and their doctors work together when starting or switching to a new medication. Researchers tested how satisfied patients and doct…