Diet showdown: can keto or mediterranean ease psoriasis and joint pain?

NCT ID NCT06164860

Completed Symptom relief Sponsor: Attikon Hospital Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether an 8-week ketogenic or Mediterranean diet could reduce inflammation in 26 adults with obesity, psoriasis, and psoriatic arthritis. Participants followed one of the two diets, and researchers measured skin severity (PASI score) and joint activity (DAPSA score), along with inflammatory markers like IL-6 and IL-17. The goal was to see if diet alone could improve symptoms beyond standard medication.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Dietary intervention (ketogenic diet or Mediterranean diet)
What this could lead to: If successful, this could show that a specific diet helps reduce skin and joint inflammation in people with obesity and psoriatic arthritis.
What could go wrong: This is a small, completed trial with only 26 participants, so results may not apply to everyone. Dietary changes can be hard to maintain long-term.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Obesity obesity disorder psoriasis psoriatic arthritis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OBESITY AND PSORIASIS

Contacts and locations

Locations

Vaia Lambadiari

Athens, Attica, 12462, Greece

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