POSTPARTUM DEPRESSION
Clinical trials for POSTPARTUM DEPRESSION explained in plain language.
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Single shot could lift postpartum depression, early trial shows
Symptom relief CompletedThis study tested a single injection of RE104 in 84 women with moderate-to-severe postpartum depression. The goal was to see if it reduces depressive symptoms better than a low-dose comparison. Results will help determine if this approach is safe and effective for new mothers.
Matched conditions: POSTPARTUM DEPRESSION
Phase: PHASE2 • Sponsor: Reunion Neuroscience Inc • Aim: Symptom relief
Last updated Jun 16, 2026 21:03 UTC
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Can a parenting group ease postpartum depression and anxiety?
Symptom relief CompletedThis study tested whether a 12-session parenting group therapy, called the Connecting and Reflecting Experience (CARE) program, is helpful and doable for new parents experiencing postpartum depression or anxiety. Seventeen parents of infants aged 3 to 12 months took part. Researc…
Matched conditions: POSTPARTUM DEPRESSION
Phase: NA • Sponsor: Montefiore Medical Center • Aim: Symptom relief
Last updated Jun 16, 2026 21:03 UTC
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New pill shows promise for severe postpartum depression in phase 2 trial
Symptom relief CompletedThis study tested an experimental oral drug called NORA520 in 93 women with severe postpartum depression. Participants took the drug or a placebo for just 3 days. Researchers measured how well the drug reduced depression symptoms and checked for side effects, as well as how much …
Matched conditions: POSTPARTUM DEPRESSION
Phase: PHASE2 • Sponsor: DuKang Pharmaceuticals, Inc. • Aim: Symptom relief
Last updated Jun 16, 2026 12:54 UTC
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Empowerment program for pregnant moms shows promise in reducing trauma and boosting Baby's health
Symptom relief CompletedThis study tested a program called the Pregnant Moms' Empowerment Program (PMEP) for pregnant women who had experienced intimate partner violence in the past year. The goal was to see if the program could improve mothers' mental health, reduce the chance of further violence, and …
Matched conditions: POSTPARTUM DEPRESSION
Phase: NA • Sponsor: University of Notre Dame • Aim: Symptom relief
Last updated Jun 16, 2026 12:49 UTC
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New drug shows promise for moms with severe Post-Baby depression
Symptom relief CompletedThis study tested a new medicine called SAGE-547 in 138 women with severe postpartum depression. The drug was given as a 60-hour IV infusion to see if it could quickly reduce depression symptoms compared to a placebo. The goal was to help new mothers feel better within days, with…
Matched conditions: POSTPARTUM DEPRESSION
Phase: PHASE3 • Sponsor: Supernus Pharmaceuticals, Inc. • Aim: Symptom relief
Last updated Jun 15, 2026 19:02 UTC
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New shot shows promise for new moms battling depression
Symptom relief CompletedThis study tested a medicine called SAGE-547 given as a 60-hour IV drip to help women with severe or moderate postpartum depression. 108 women took part, and researchers measured changes in depression scores compared to a placebo. The goal was to see if the drug could quickly eas…
Matched conditions: POSTPARTUM DEPRESSION
Phase: PHASE3 • Sponsor: Supernus Pharmaceuticals, Inc. • Aim: Symptom relief
Last updated Jun 15, 2026 18:56 UTC
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Postpartum depression drug may be safe to use at home, study finds
Symptom relief CompletedThis study looked at whether the drug ZULRESSO (brexanolone) can be safely given at home to women with postpartum depression. Fifty-two women took part, and researchers tracked side effects that caused the treatment to be stopped or interrupted. The goal was to see if home use is…
Matched conditions: POSTPARTUM DEPRESSION
Phase: PHASE4 • Sponsor: Supernus Pharmaceuticals, Inc. • Aim: Symptom relief
Last updated Jun 15, 2026 18:54 UTC
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Talking therapy shows promise for postpartum depression and bonding
Symptom relief CompletedThis study tested a special educational program for pregnant women to see if it could lower depression after childbirth and strengthen the bond between mother and baby. 88 women in their 20th to 35th week of pregnancy took part. The program was based on the Watson Human Caring Mo…
Matched conditions: POSTPARTUM DEPRESSION
Phase: NA • Sponsor: Yasemin Ozhuner • Aim: Symptom relief
Last updated Jun 01, 2026 18:08 UTC
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Hormone withdrawal after pregnancy linked to mood symptoms in new study
Knowledge-focused CompletedThis study looked at whether the drop in pregnancy hormones after childbirth triggers mood problems in women who have had postpartum depression before. Researchers created a temporary hormone environment similar to pregnancy and then stopped it to see how mood changed. The goal w…
Matched conditions: POSTPARTUM DEPRESSION
Phase: PHASE2 • Sponsor: National Institute of Mental Health (NIMH) • Aim: Knowledge-focused
Last updated Jun 16, 2026 12:48 UTC