POSTOPERATIVE PAIN, ACUTE

This study tests whether a specific nerve block, given before surgery, can reduce pain and the need for strong painkillers (opioids) in teenagers having ear reconstruction using rib cartilage. Sixty teens aged 13 to 18 will be randomly assigned to receive either the nerve block o…

This study compares a long-acting painkiller (liposomal bupivacaine) to a standard one for pain after lung surgery. About 210 adults having keyhole lung surgery will be randomly assigned to receive one of the two painkillers or no nerve block. The goal is to see if the long-actin…

This study tests if a specific nerve block (SPSIP block) can reduce pain after arthroscopic shoulder surgery. About 80 adults having elective shoulder surgery will receive this block or standard care. The main goal is to see if it lowers the amount of opioid pain medicine needed …

This study looks at whether starting gentle, supervised movement soon after obesity surgery and continuing it at home can help manage pain and speed up recovery. About 112 adults who can read Danish will take part. Researchers will measure pain, physical function, and quality of …

This study is testing whether a special nerve block (PENG block) given before hip replacement surgery can help reduce pain, lower the need for strong painkillers, and help patients get moving sooner. About 60 adults aged 40-85 who are having hip replacement will take part. The go…

This study aims to find the most effective dose of morphine given into the spinal fluid to control pain after a C-section. Researchers will test different doses in 100 healthy women having planned C-sections, adjusting the dose based on how well the previous participant's pain wa…

This study tests a new pain medicine called PF614 for people who have moderate to severe pain after a tummy tuck (abdominoplasty). About 320 adults will take either PF614 or a placebo before surgery and every 12 hours for up to 4 days. Researchers will measure pain levels and how…

This study looks at whether meloxicam, a different type of pain reliever, works better than the usual ibuprofen for pain after Mohs skin cancer surgery. About 300 adults having Mohs surgery will be split into three groups: one gets a low dose of meloxicam, another a higher dose, …

This study looks at whether giving the painkiller nalbuphine at different times during knee replacement surgery can better control pain and keep the heart stable in patients aged 65 and older. About 162 participants will receive the same dose of nalbuphine either before, during, …

This study tests whether giving the painkiller ketorolac directly into the blood flow of a leg (while a tourniquet is on) can extend pain relief after lower limb orthopedic surgery. About 76 adults having elective leg surgery under spinal anesthesia will be randomly assigned to r…

This study compares two ways to block pain during lung surgery (VATS) to see if they can prevent chronic pain that lasts for months. Forty adults having planned lung surgery will receive either an ultrasound-guided nerve block or a surgeon-given block. Researchers will track pain…